Dopamine was initially regarded as a mere precursor of noradrenaline, but has progressively gained its present status of a common target for major drug classes and a substrate for some basic functions and dysfunctions of the Central Nervous System. The scientific interest has shifted from typically motor areas of the striatum to traditionally limbic ones as the nucleus accumbens and its afferent areas, the prefrontal cortex, the hippocampal formation and the basolateral amygdala. This double volume provides a systematic account of the anatomy, physiology, neurochemistry, molecular biology and behavioural pharmacology of dopamine in the CNS. The second volume deals with functional and behavioural aspects as the electrophysiology of dopamine neurons and of dopamine actions, the interaction with other transmitters and its role in behaviour and in the action of centrally acting drugs.

13 Electrophysiological Pharmacology of Mesencephalic Dopaminergic Neurons

14 Presynaptic Regulation of Dopamine Release
15 Dopamine - Acetylcholine Interactions
16 Dopamine - Glutamate Interactions
17 Dopamine - Adenosine Interactions
18 Dopamine - GABA Interactions
19 Dopamine - Its Role in Behaviour and Cognition in Experimental Animals and Humans
20 Molecular Knockout Approach to the Study of Brain Dopamine Function
21 Behavioural Pharmacology of Dopamine D2 and D3 Receptors: Use of the Knock-out Mice Approach
22 Dopamine and Reward
23 Molecular and Cellular Events Regulating Dopamine Neuron Survival
24 Dopamine and Depression
25 Dopamine in Schizophrenia Dysfunctional Information Processing in Basal Ganglia - Thalamocortical Split Circuits
26 Atypical Antipsychotics
27 Sleep and Wake Cycle.