Dynamics of the Mammalian Sperm Head

Modifications and Maturation Events From Spermatogenesis to Egg Activation

Dynamics of the Mammalian Sperm Head

Modifications and Maturation Events From Spermatogenesis to Egg Activation

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Mammalian spermatozoa have complex structures. The structure-function relationship of sperm has been studied from various viewpoints. Accumulated evidence has shown that the sperm components undergo sequential changes from the beginning of spermatogenesis to the time of fertilization/embryogenesis. Structural analyses have been performed using various new techniques of light and electron microscopy as well as immunohistochemistry and immunocytochemistry in combination with specific probes such as antibodies against sperm components. Recently developed gene-manipulation techniques have accelerated investigations on the events that govern the relationship between the structure and molecular components of sperm. In addition, animal models with gene manipulations have been shown to exhibit various morphological and functional abnormalities that lead to infertility.

In this book, I discuss the events that occur in the normal sperm head and govern the structure-function relationship from the time of spermatogenesis to that of fertilization or egg activation. In this regard, I describe dynamic modifications and maturation events occurring in sperm-head components and compare the outcomes of these events with the outcomes of their failure.



Mammalian sperm head
Sperm-Head Formation and Factors Affecting It
Post-testicular modifications and maturation events occurring in the sperm
Dynamics of the acrosome
Dynamics of the perinuclear theca
Dynamics of the sperm nucleus
Dynamics of the membrane system
Dynamics of egg (oocyte) activation
Status of sperm-head components during normal fertilization, IVF, ICSI, and
CONCLUSION.
ISBN 978-3-540-89978-5
Artikelnummer 9783540899785
Medientyp Buch
Copyrightjahr 2009
Verlag Springer, Berlin
Umfang X, 98 Seiten
Abbildungen X, 98 p. 36 illus., 7 illus. in color.
Sprache Englisch