Enantioselective Catalysis

From Principles to Industrial Production

Enantioselective Catalysis

From Principles to Industrial Production

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Enantioselective or asymmetric catalysis is considered the supreme discipline in organic chemistry. It is widely used in modern laboratory synthesis and industrial production processes of bioactive molecules, e.g. pharmaceuticals. This book provides thorough knowledge for students, scientists and beginners in industry on all important aspects, from basic principles to industrial application.

From the Contents:

Basic Principles:
- History and Definitions
- Enantioselective Synthesis and Catalysis
- Stereochemistry

Reductions:
- Concerted Hydrogen/ Alkene Addition
- Heterogeneous Sabatier-Hydrogenation
- Homogeneous Hydrogenation: Wilkinson-Hydrogenation, Noyori's BINAP-Hydrogenation, Corey-Bakshi-Shibata-Reduction

Oxidations:
- Katsuki-Sharpless-Assymetric-Epoxidation
- Jacobsen-Asymmetric-Epoxidation
- Sharpless-Assymetric-Dihydroxylation
- Oxon-Epoxidation

C-C Bond-Formation:
- Addition Reactions to Carbonyls
- Enantioselective Cross-Coupling
- Allylic Substitution
- Organo-Catalysis

C-Het Bond-Formation:
- Enantioselective Acylation
- Kinetic Racemate Resolution

ISBN 9783110340402
Artikelnummer 9783110340402
Medientyp Buch
Copyrightjahr 2025
Verlag De Gruyter
Umfang X, 300 Seiten
Abbildungen 150 b/w and 50 col. ill., 100 b/w tbl.
Sprache Englisch