At the beginning of the 20^th century, life expectancy at birth in North America and Western Europe was around 50 years of age. Nowadays, women have gained more than 30 years of age and men are trailing closer. However, according to several sociologists such as Louis Chauvel, the notion of a "greying society" is not entirely adequate since aging people are physically and socially younger and more active for a longer time. Of course, the other side of the medal is to tackle the challenge of preventing age-associated chronic diseases. In this book the extensive field of research on neuroendocrine aging has been reviewed. Aging is one of the most complex biological processes determined by the interactions between genetic and environmental factors.

Regulation of C. elegans Life Span by Insulin-Like Signaling

IGF-1 and Insulin Signaling in the Control of Longevity
IGF-1 Receptors in Mammalian Longevity: Less is More
IGF-1 Gene Polymorphism and Disease in the Elderly
Polymorphisms and Male Ageing
Age-Related Changes in the Regulation of the Hypothalamic-Pituitary Adrenal Axis: the Role of Personality Variables
Aging White Matter and Cognitive Decline: A Role for Steroids
How Do Changes in the GH/IGF-1 Status of the Elderly - Whether Occurring Naturally, Pathologically or Therapeutically Induced - Impact Their Lives?
Estrogen and Cognitive Functioning in Women
Genetic Polymorphisms and Age-Related Diseases: the Example of Osteoporosis
Are Estrogens Protective or Risk Factors in the Brain? Insights Derived from Animal Models
Testosterone Supplementation and Aging-Associated Sarcopenia
The Long Thread of GFAP in Aging, Steroids, and Synaptic Plasticity
Circadian Rhythmicity and Aging: The Molecular Basis of Oscillatory Gene Expression
Prediction of Death in the Elderly Men: Endocrine Factors.