Endocrine Surgery in Children

Endocrine Surgery in Children

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This book provides in-depth practical advice on how to manage children with endocrine conditions that may benefit from surgery. It is more detailed than general pediatric surgery texts and more surgically oriented than endocrinology texts. The first section is devoted to the thyroid and parathyroid, with detailed discussion of thyroid nodules, thyroid cancer, hyperthyroidism, hyperparathyroidism, and multiple endocrine neoplasia. The second section on the pancreas focuses on nesidioblastosis, islet cell transplantation, the surgical treatment of diabetes, and surgical complications of diabetes. Adrenal disorders are then discussed, followed by a section on the evaluation and management of ovarian and testicular torsion and tumors. The closing section addresses miscellaneous topics such as gynecomastia in boys and growth restriction surgery. This book will serve as an invaluable reference for all practitioners and trainees who care for children with endocrine problems for which surgery is considered.


<p><b>Endocrine Surgery in Children</b></p><p><b> </b></p><p> </p><p>Daniel J. Ledbetter, MD, FACS, FAAP</p><p>Professor of Surgery</p><p>University of Washington</p><p>Attending Surgeon</p><p>Seattle Children's Hospital</p><p>Seattle, Washington, USA</p><p> </p><p>Paul R. V. Johnson, MBChB, MD, FRCS(Eng), FRCS (Edin), FRCS (Paed.Surg), FAAP</p><p>Professor of Pediatric Surgery</p><p>University of Oxford</p><p>Director of the Oxford Islet Transplant Programme</p><p>Academic Pediatric Surgery Unit</p><p>Nuffield Department of Surgical Sciences</p><p>John Radcliffe Hospital</p><p>Oxford, UK </p><p><b> </b></p><b><br> </b> <p><b> </b></p><p><b> </b></p><p><b>Foreword</b></p><p><b> </b></p><p>Endocrine conditions requiring surgery in children are extremely rare. Surgeons undertaking this surgery need to be specifically trained and exposed to a large volume of cases in order to maintain their expertise. Therefore it is clear that the surgery needs to be concentrated in designated regional centres and carried out by a select number of paediatric surgeons. In addition, a close working relationship with the paediatric endocrinologists is essential for the overall wellbeing of the child.</p><p>While management of many of these conditions must remain within the armamentarium of the paediatric surgeon, for example neuroblastoma, hyperinsulinism, adrenal tumours and gonadal conditions, there is a tendency to engage adult endocrine surgeons with specific expertise in a particular organ, such as thyroid, parathyroid, pituitary, to perform the procedures in conjunction with the paediatric surgeons. In the latter situation, it is important that the overall care of the child should remain firmly in the province of the paediatric specialist. </p><p>This book devoted to the surgery of endocrine disorders in children fills a major gap in the paediatric surgical literature and brings together the full range of endocrine conditions encountered in the paediatric age range. The last publication devote to the surgery of endocrine disorders in children was part of the Progress in Pediatric Surgery series (now discontinued) published in 1991. </p><p>This publication includes contributions from international authorities in paediatric surgery and endocrinology, mainly from the United Kingdom and North America and should be viewed as the standard text for many years to come.</p><p> </p><p>Lewis Spitz MD, PhD, FRCS(Edin, Eng, I), FRCHCP, FAAP, FCS(SA), FACS</p><p>Emeritus Nuffield Professor of Paediatric Surgery</p><p>Institute of Child Health, University College, London</p><p>Hon. Consultant Paediatric Surgeon</p>Great Ormond Street Hospital NHS Trust <p></p><p>London, UK</p><p> </p><b><br> </b> <p><b> </b></p><p><b>Preface</b></p><p><b> </b></p><p>Endocrine surgical conditions during childhood are relatively rare. However, they represent an interesting and challenging group of conditions that all Pediatric Surgeons will encounter sometime during their careers. This book is one of the first to provide a specific overview of the range of different endocrine surgical conditions encountered in children, together with their management.  It is aimed at any surgeon operating on endocrine conditions in children and adolescents. <b></b></p><p> . </p><p>The book is divided into sections based on the different endocrine organs. Each section begins with a chapter outlining the embryology, anatomy, and physiology of that organ, before subsequent chapters address the different surgical conditions that occur, together with their diagnosis, management, and outcomes. Basic science and 'state of the art' research perspectives are included as they relate to surgical decision-making and optimal clinical care. We have intentionally chosen a diverse group of authors who have experience and expertise in caring for children with endocrine surgical conditions in North America and in the UK. The authors include endocrinologists, adult endocrine surgeons, and paediatric surgeons, and represent many who are at the forefront of both clinical care and cutting edge research. One of the key messages that comes out throughout the book is that rare endocrine surgical conditions require a collaborative multi-disciplinary team approach to ensure that the children receive the very best management resulting in the most favourable outcomes.</p><p> </p><p>It is our hope that this international, multidisciplinary perspective will give surgeons caring for children with endocrine conditions requiring surgery, additional insights that will lead to a better understanding of the conditions and ultimately improved patient care.</p><p> </p><p><i>Dan Ledbetter and Paul Johnson </i></p><p> </p><p> </p><br> <p> </p><p> </p><p><b>Dedication</b></p><p> </p><p>To Sunny, Kelly, and Brian - the greatest joys of my life.</p><p>DJL</p><p> </p><p>To Hilary, Thomas, and Tilly - for your unconditional love, support, and patience during the preparation of this book. </p><p>PRVJ</p><p><b> </b></p><b><br> </b> <b> </b><p></p><p><b>Acknowledgments</b></p><p> </p><p>We want to thank the many people who have directly and indirectly contributed to this book. First, we would like to thank our mentors who stimulated our interests in pediatric endocrine surgery. These include the late David Tapper and the late Nick Dudley, both of whom demonstrated excellence in the operative care of children. Next, Diana Farmer, who persuaded the American College of Surgeons that a panel discussion of endocrine problems in children deserved a place on the program of its annual Clinical Congress. That panel discussion was the primary inspiration for this book.  </p><p> </p><p>Next, we would like to thank Springer, who supported this book through its long gestation to publication. In particular we would like to thank Margaret Burns who guided the book throughout its development to the point of completion.</p>We would also like to thank all the contributing authors. They have shown remarkable patience throughout the production of the book and without them this book would clearly not have been possible. <p></p><p> </p><p>We would like to thank all our excellent clinical colleagues in Anesthesia, Surgery, Pathology, Radiology, Endocrinology, and Oncology at both Seattle Children's Hospital and the Children's Hospital in Oxford who have helped care for the many and varied patients with endocrine problems who have needed surgery. This includes pediatric surgical colleagues in the Division of Pediatric General and Thoracic Surgery in Seattle (Robert Sawin, John Waldhausen, Pat Healey, Adam Goldin, Ken Gow, John Meehan, George Drugas, Jeff Avansino, Patrick Javid, and Kim Riehle) and in the Department of Paediatric Surgery , Endocrinology, and Endocrine Surgery in Oxford (Hugh Grant, Kokila Lakhoo, Silke Wagener, Alex Lee, Ian Willetts, Rosa Romero, Radu Mihai, Fiona Ryan, and Taffy Makayer). Finally, we would like to thank all the surgical trainees including residents, fellows, core trainees, and registrars who do much of the work in the hospital, but more importantly, ask many of the most important questions that inspire everyone to discover new and better ways to care for children. </p><p> </p><br> <p> </p><p> </p><p>Foreword</p><p>Preface</p><p>Dedication</p><p>Acknowledgments</p><p>Contributors</p><p><b>I. Thyroid</b></p><p>1. Thyroid Gland Embryology, Anatomy, and Physiology</p><p>Gerard Walls and Radu Mihai </p><p>2. Hyperthyroidism</p><p>Betty Panayota Messazos, Radu Mihai, and Fiona Jane Ryan</p><p>3. Thyroid Nodules in Children</p><p>Geoffrey K. Blair and Daniel J. Ledbetter</p><p>4. Thyroid Cancer in Children</p><p>Daniel J. Ledbetter</p><p><b>II. Parathyroid</b></p><p>5. Parathyroid Gland Embryology, Anatomy, and Physiology</p><p>Gerard Walls and Radu Mihai </p><p>6. Parathyroid Surgery in Children</p><p>Jocelyn Burke, Herbert Chen, and Ankush Gosain</p><p><b>III. Adrenal</b></p><p>7. Adrenal Gland Embryology, Anatomy, and Physiology</p><p>Sanjeev Vasudevan and Mary L. Brandt</p>8. Phaeochromocytoma<p></p><p>Michael J. Stechman and Gregory P. Sadler </p><p>9. Neuroblastoma</p><p>Keith Holmes</p><p>10. The Evaluation and Management of Adrenal Masses and Adrenocortical Tumors </p><p>Kenneth W. Gow</p><p><b>IV. Pancreas</b></p><p>11. Pancreas Embryology, Anatomy, and Physiology </p><p>Yousef El-Gohary and George K. Gittes<sup></sup></p><p>12. Congenital Hyperinsulinism</p><p>Khalid Hussain, Shireen A. Nah, and Agostino Pierro<sup></sup></p><p>13. Pancreatic Neuroendocrine Tumors</p><p>Paul R. V. Johnson</p><p>14. Islet Cell Transplantation </p><p>Antonio Bruni, Michael McCall, and A. M. James Shapiro </p><p>15. Diabetes in the Pediatric Surgical Patient</p><p>Ari J. Wassner and Michael S. D. Agus</p><p><b>V. Bariatric Surgery</b></p><p>16. Assessing and Selecting Patients for Bariatric Surgery</p><p>Thomas H. Inge</p><p>17. Bariatric Surgery in Children</p><p>Mansoor Ali Khan and Roger Ackroyd </p><p><b>VI. Ovary, Testicles, and Fertility</b></p><p>18. Pathogenesis and Treatment of Disorders of Sexual Development</p><p>Rafael V. Pieretti</p>19. Testis Embryology, Anatomy, and Physiology <p></p><p>John Hutson</p><p>20. Surgical Considerations of Testicular Maldescent</p><p>John Hutson</p><p>21. Testicular Torsion</p><p>Daniel W. Colliver and David F. M. Thomas</p><p>22. Testicular Tumors in Children</p><p>Yaser El-Hout and Darius J. Bägli</p><p>23. Ovarian Embryology, Anatomy, and Physiology Including Normal Menstrual Physiology<</p><p>Nancy Sokkary and Jennifer E. Dietrich </p><p>24. Ovarian Tumors in Children</p><p>David F. M. Thomas</p><p>25. Ovarian Torsion</p><p>Anne C. Fischer</p><p>26. Fertility Preservation</p><p>Jennia Michaeli, Stephen Kennedy, and Ariel Revel</p><p><b>VII. Breast</b></p><p>27. Breast Embryology, Anatomy, and Physiology </p><p>Monica E. Lopez and Oluyinka O. Olutoye</p>28. Paediatric and Adolescent Breast Disorders <p>Clare M. Rees, Kokila Lakhoo, and P. G. Roy</p><p>29. Gynecomastia </p><p>Tim Goodacre and Gavin McCoubrey</p><p><b>VIII. Miscellaneous</b></p><p>30. Multiple Endocrine Neoplasia Type 1 and Type 4</p><p>Gerard V. Walls</p><p>31. Multiple Endocrine Neoplasia Type 2</p><p>Eduardo A. Perez and Michael Skinner</p><p><b>IX. Pituitary</b></p><p>32. Pituitary Gland Embyology, Anatomy, and Physiology</p><p>Vaitsa Tziaferi and Mehul T. Dattani</p><p>33. Surgical Considerations of the Pituitary </p><p>Toba Niazi and Samuel R. Browd</p><p> </p><p> </p><p> </p><br> <p> </p><p> </p><b>Contributors</b><p></p><p> </p><p>Roger Ackroyd, MBChB, MD(Distinction), FRCS(Eng), FRCS(Ed), FRCS(Gen Surg) </p><p>Department of General Surgery, Northern General Hospital, Sheffield, South Yorkshire, UK </p><p> </p><p>Michael S. D. Agus, MD</p><p>Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA  USA </p><p> </p><p>Darius J. Bägli, MDCM, FRCSC, FAAP, FACS </p><p>Department of Surgery, Division of Urology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada </p><p> </p><p>Geoffrey K. Blair, MD, FRCSC</p><p>Division of Pediatric Surgery, British Columbia's Children's Hospital, Vancouver, British Columbia, Canada </p><p> </p><p>Mary L. Brandt, MD</p>Division of Pediatric Surgery, Department of Surgery, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA <p></p><p> </p><p>Samuel R. Browd, MD, PhD, Facs, Faans, Faap</p><p>Department of Neurological Surgery, University of Washington, Seattle, WA, USA </p><p> </p><p>Antonio Bruni, BSc</p><p>Li Ka Shing Centre for Health Research Innovation, Edmonton, Alberta, Canada </p><p> </p><p>Jocelyn Burke, MD</p><p>Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA </p><p> </p><p>Herbert Chen, MD</p><p>Department of Surgery, Division of General Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA </p><p> </p><p>Daniel W. Colliver, FRCS</p><p>Department of Paediatric Surgery and Urology, Queens Medical Centre, Nottingham, UK </p><p> </p><p>Mehul T. Dattani, MBBS, MD, FRCPCH, FRCP</p><p>Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit, UCL Institute of Child Health and Great Ormond Street Hospital for Children, London, UK </p><p> </p><p>Jennifer E. Dietrich, MD, MSc </p><p>Department of Pediatric and Adolescent Gynecology, Texas Children's Hospital, Houston, TX, USA </p><p> </p><p>Yousef El-Gohary, MD, MRCS (Glasg)</p><p>Department of Surgery, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA </p><p> </p><p>Yaser El-Hout, MD</p><p>Division of Urology, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon </p><p> </p><p>Anne C. Fischer, MD, PhD</p><p>Department of Pediatric Surgery, Tenet Florida Physician Services, West Palm Beach, FL, USA  </p><p> </p><p>George K. Gittes, MD<sup></sup></p><p>Department of Pediatric Surgery and Surgery, Children's Hospital of Pittsburgh; Division of Pediatric Surgery, University of Pittsburgh, School of Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA </p><p> </p><p>Tim Goodacre, FRCS, BSc, MB, BS  </p><p>Nuffield Department of Surgery, University of Oxford, Oxford, UK</p><p> </p><p>Ankush Gosain, MD, PhD</p><p>Department of Surgery, Division of Pediatric Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA </p><p> </p><p>Kenneth W. Gow, MD</p><p>Department of General and Thoracic Surgery, Seattle Children's Hospital and the University of Washington, Seattle, WA, USA </p><p> </p><p>Keith Holmes, ChM, FRCS, DCH</p><p>Department of Paediatric Surgery, St. George's Hosptial, London, UK  </p><p> </p><p>Khalid Hussain, MBChB, MRCP, MSc</p><p>Developmental Endocrinology Research Group, Clinical and Molecular Genetics Unit, Institute of Child Health/Great Ormond Street Hospital for Children, University College London, London, UK </p><p> </p><p>John Hutson, MD</p><p>Department of Paediatrics, University of Melbourne; Department of Urology, Royal Children's Hospital, Melbourne; Douglas Stephens Surgical Research Laboratory, Murdoch Childrens Research Institute, Melbourne Royal Children's Hospital, Parkville, Victoria, Australia < </p><p>Thomas H. Inge, MD, PhD, FACS, FAAP</p><p>Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA </p><p> </p><p>Paul R. V. Johnson, MBChB, MD, FRCS(Eng), FRCS (Edin), FRCS (Paed.Surg), FAAP</p><p>Department of Pediatric Surgery, University of Oxford; Oxford Islet Transplant Programme, Academic Pediatric Surgery Unit, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, UK </p><p> </p><p>Stephen Kennedy, MA (Oxon), MD, MRCOG</p><p>Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, Oxford, UK </p><p> </p><p>Mansoor </p><p>General Military Royal Centre for Defence Medicine; Department of Surgery and Trauma, Imperial College London. London, UK </p><p> </p><p>Kokila Lakhoo, PhD, FRCS(Eng & Edin), FCS(SA), MRCPCH(UK), MBChB</p><p>Department of Paediatric Surgery, Children's Hospital Oxford, Oxford Radcliffe Hospitals NHS Trust, Oxford, UK </p><p> </p>Monica E. Lopez, MD<p></p><p>Department of Pediatric Surgery, Texas Children's Hospital, Houston, TX</p><p> </p><p>Daniel J. Ledbetter, MD, FACS, FAAP</p><p>Department of Surgery, University of Washington; Department of Surgery, Seattle Children's Hospital, Seattle, WA, USA </p><p> </p><p>Michael McCall, MD, PhD </p><p>Department of Surgery, Royal Alexandra Hospital, Edmonton, Alberta, Canada </p><p> </p><p>Gavin McCoubrey</p><p>Department of Plastic Surgery, Salisbury NHS Foundation Trust, Salisbruy, Wiltshire, UK</p><p> </p><p>Betty Panayota Messazos, MBBChir, MA, MRCPCH</p><p>Department of Paediatric Endocrinology, Oxford Children's Hospital, Oxford University Hospitals NHS Trust, Oxford, UK </p><p> </p><p>Jennia Michaeli, MD</p><p>Department of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University-Hadassah Medical School, Jerusalem, Israel </p><p> </p><p>Radu Mihai, MD, PhD, FRCS</p>Department of Surgery, John Radcliffe Hospital, Oxford, UK <p></p><p> </p><p>Shireen A. Nah, MBBS, MRCS, MS </p><p>The Surgery Unit, UCL Institute of Child Health, University College London and Great Ormond Street Hospital for Children, NHS Trust, London, UK</p><p> </p><p>Toba Niazi, MD</p><p>Department of Clinical Neurological Surgery and Pediatrics, University of Miami, Miami, FL, USA</p><p> </p><p>Oluyinka O. Olutoye, MD, PhD</p><p>Texas Children's Fetal Center, Texas Children's Hospital, Houston, TX, USA </p><p> </p><p>Eduardo Perez, MD</p><p>Division of Pediatric Surgery, The Dewitt Daughtry Family Department of Surgery, University of Miami, Miller School of Medicine, Miami, FL, USA </p><p> </p><p>Rafael V. Pieretti, MD</p><p>Department of Pediatric Surgery, MassGeneral Hospital for Children, Boston, MA, USA</p><p> </p><p>Agostino Pierro, MD, FRCS (Eng), FRCS(Ed), FAAP<sup></sup></p><p>Department of Pediatric General and Thoracic Surgery, Hospital for Sick Children, Toronto, Ontario, Canada </p><p> </p><p>Clare M. Rees, MD, MRCS, MBChB</p><p>Department of Paediatric Surgery, Children's Hospital Oxford, Oxford Radcliffe Hospitals NHS Trust, Headington, UK </p><p> </p><p>Ariel Revel, MD</p><p>Department of Obstetrics and Gynecology, Hadassah Medical Center and Hebrew University-Hadassah Medical School, Jerusalem, Israel </p><p> </p><p>P. G. Roy, MBBS, MS (Gen Surg), MD, FRCS (Glas), FRCS (Gen Surg)</p><p>Department of Breast Surgery, Churchill Hospital, Oxford, UK </p><p> </p><p>Fiona Jane Ryan, MD</p><p>Department of Paediatric Endocrinology, Oxford Children's Hospital, Oxford, UK </p><p> </p><p>Gregory P. Sadler, MD, FRCS</p><p>Department of Endocrine Surgery, John Radcliffe Hospital, Headley Way, Oxford, UK</p><p> </p><p>A. M. James Shapiro, MD, PhD</p><p>Departments of Surgery, Medicine and Surgical Oncology, and Clinical Islet and Living Donor Liver Transplant Programs, University of Alberta, </p><p> </p><p>Michael A. Skinner, MD</p><p>Department of Pediatric Surgery, University of Texas Southwestern Medical Center; Children's Medical Center, Dallas, TX, USA </p><p> </p><p>Nancy Sokkary, MD </p><p>Department of Pediatrics, UNM Children's Hospital, The University of New Mexico, Albuquerque, NM, USA </p><p> </p><p>Michael J. Stechman, MD, FRCS</p><p>Department of Endocrine Surgery, University Hospital of Wales, Heath Park, Cardiff, UK</p><p> </p><p>David F. M. Thomas, FRCP, FRCPCH, FRCS</p><p>Department of Paediatric Urology, Leeds Teaching Hospitals and University of Leeds, Leeds, UK </p><p> </p><p>Vaitsa Tziaferi, MD, MRCPCH, MSc</p><p>Department of Paediatric Endocrinology, Great Ormaond Street Hospital, London, UK </p> <p></p><p>Sanjeev Vasudevan, MD </p><p>Department of Pediatric Surgery, Texas Children's Hospital, Houston, TX, USA </p><p> </p><p>Gerard Walls, MB, BS, MRCS </p><p>General and Endocrine Surgery, University Hospitals of Morecambe Bay, NHS Foundation Trust, Lancaster, UK </p><p> </p><p>Ari J. Wassner, MD</p><p>Department of Pediatrics, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA </p><p> </p>
ISBN 978-3-662-54254-5
Artikelnummer 9783662542545
Medientyp Buch
Auflage 1st ed. 2018
Copyrightjahr 2017
Verlag Springer, Berlin
Umfang XX, 462 Seiten
Abbildungen XX, 462 p. 116 illus., 35 illus. in color.
Sprache Englisch