The development of accurate hormonal assays in recent years has evoked much interest in the area of anaesthesia and surgery. In an effort to allow an exchange of ideas and new information in this area, the First International Symposium on Endocrinology in Anaesthesia and Surgery was held in Bonn during September 1978. The contents of this book represent much of the information presented by the leading authorities in this field. The presentations were grouped in three areas: 1. Basic problems of endocrinology in anaesthesia and surgery; 2. The response of the endocrine system to anaesthesia and surgery; 3. Hormone and anaesthetic management of endocrine disease. As with any multi-authored text, there is both repetition and diversity but hopefully the reader will be able to obtain much of the useful information. As Editors, we wish to express our deep appreciation to Profes sor R. Frey and Springer-Verlag for including this book in the series on "Anaesthesiology and Intensive Care Medicine". H. Stoeckel T. Oyama Table of Contents I. Basic Problems of Endocrinology in Anaesthesia and Surgery H. Breuer Basic Principles Regulating the Endocrine System . . . . . . . .. 3 G. Wesemann and E. Grote Pathophysiology of Intra- and Postoperative Stress .. . . . . .. 10 M. Trede Surgical Treatment of Endocrine Disorders .. . . . . . . . . . .. 24 T. Oyama Influence of Anaesthesia on the Endocrine System ... . . . .. 39 L. Nocke-Finck Radioimmunological Determination of Hormones.

I. Basic Problems of Endocrinology in Anaesthesia and Surgery

Basic Principles Regulating the Endocrine System
Pathophysiology of Intra- and Postoperative Stress
Surgical Treatment of Endocrine Disorders
Influence of Anaesthesia on the Endocrine System
Radioimmunological Determination of Hormones. Applicability and Evaluation in Severely Ill Patients
Isotope Dilution - Mass Spectrometry. A Definitive Method for the Determination of Hormones
II. Effects of Anaesthesia and Surgery on the Endocrine System
Effects of Anaesthesia and Surgery on Catecholamines
The Effect of Anaesthesia on Antidiuretic Hormone Levels
Effect of Anaesthesia and Surgery on the Renin-Angiotensin-Aldosterone System
Intraoperative Fluids and Hormonal Harmony
The Influence of Anaesthesia on Prolactin Secretion in Man
Influence of Neurogenic Blockade on the Endocrine Metabolic Response to Surgery
The Effect of Anaesthesia and Surgery on Sex Hormones
III. Hormonal and Anaesthetic Management of Endocrine Diseases
Hormonal Aspects of Hypertension
Diagnosis and Perioperative Management of Pheochromocytoma
Anaesthetic Management of Steriod-treated Patients
Anaesthetic Management of Hypophysectomy
Consequences of Parathyroid Surgery
Thymectomy in Myasthenia Gravis: Pre- and Postoperative Treatment
Endocrine and Exocrine Treatment After Pancreatectomy
Shock and Endocrine Function
Renin- and Aldosterone-Regulation in Hepatic Coma Treated by Baboon Liver Perfusion and in Prolonged Shock
Advantages and Disadvantages of Proteinanabolica.