This book provides a comprehensive and up-to-date overview of current endoscopic ultrasound use in all aspects of pancreatology, from diagnosis to therapy, i.e., from tissue acquisition, with standard fine-needle aspiration and the newer biopsy needles, to less invasive techniques such as contrast-enhanced ultrasound and elastography. It also covers novel therapeutic strategies, with a particular focus on ablative treatments and lumen-apposing stents, and describes techniques developed by the editors, in particular combined celiac plexus neurolysis with pancreatic tumor ethanol ablation and elastography-guided fine-needle aspiration. All topics are developed by pursuing an evidence-based approach and several recent meta-analyses, the majority of which were published by the authors. Due to several recent advances in the field, endoscopic ultrasound has taken on a pivotal role in the diagnosis, staging, and treatment of pancreatic lesions; as such, the present volume offers an invaluable tool for staying abreast of the state-of-the-art in this field. 

Foreword. Preface. Overview on pancreatic masses and cystic lesions. Overview on inflammatory pancreatic fluid collections. Contrast-enhanced endoscopic ultrasound and EUS elastography. Endoscopic ultrasound-guided tissue acquisition of pancreatic lesions. Evidence-based assessment of diagnostic performance of currently available needles for EUS-guided tissue acquisition. Role of EUS sampling in cystic lesions. Endoscopic Ultrasound-Guided Drainage of Pancreatic Fluid Collections. Lumen-apposing metal stents: an important step forward in the management of pancreatic fluid collections. Endoscopic pancreatic necrosectomy. Role of endoscopic ultrasound in pancreatic cancer screening. Endoscopic ultrasound in pancreatic cancer staging. Endoscopic ultrasound-guided fiducial placement. Endoscopic ultrasound-guided therapies for solid pancreatic tumors. Endoscopic ultrasound-guided pancreatic cyst ablation. Celiac plexus block and neurolysis. Interventional endoscopic ultrasound in patients on antithrombotic therapy. Sedation in patients undergoing EUS interventional procedures. Management and prevention of complications after EUS interventional procedures in pancreatic solid lesions. Quality indicators in interventional endoscopic ultrasound. Conclusive remarks and new perspectives.