Today, as the large international genome sequence projects are gaining a great amount of public attention and huge sequence data bases are created it be comes more and more obvious that we are very limited in our ability to access functional data for the gene products - the proteins, in particular for enzymes. Those data are inherently very difficult to collect, interpret and standardize as they are highly distributed among journals from different fields and are often sub ject to experimental conditions. Nevertheless a systematic collection is essential for our interpretation of the genome information and more so for possible appli cations of that knowledge in the fields of medicine, agriculture, etc .. Recent pro gress on enzyme immobilization, enzyme production, enzyme inhibition, coen zyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. It is the functional profile of an enzyme that enables a biologist of physician to analyze a metabolic pathway and its disturbance; it is the substrate specificity of an enzyme which tells an analytical biochemist how to design an assay; it is the stability, specificity and efficiency of an enzyme which determines its usefulness in the biotechnical transformation of a molecule. And the sum of all these data will have to be considered when the designer of artificial biocatalysts has to choose the optimum prototype to start with.

Dimethylallyltranstransferase

Thiamine pyridinylase
Thiamine-phosphate pyrophosphorylase
Adenosylmethionine cyclotransferase
Galactose-6-sulfurylase
Methionine adenosyltransferase
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
tRNA isopentenyltransferase
Riboflavin synthase
Geranyltranstransferase
trans-Octaprenyltranstransferase
Dihydropteroate synthase
Spermidine synthase
Cob(I)alamin adenosyltransferase
Glutathione transferase
3-Phosphoshikimate 1-carboxyvinyltransferase
Rubber cis-polyprenylcistransferase
Farnesyl-diphosphate farnesyltransferase
Spermine synthase
Sym-Norspermidine synthase
Discadenine synthase
tRNA-uridine aminocarboxypropyltransferase
Alkylglycerone-phosphate synthase
Adenylate isopentenyltransferase
Dimethylallylcistransferase
Farnesyltranstransferase
trans-Hexaprenyltranstransferase
di-trans,poly-cis-Decaprenylcistransferase
Geranylgeranyl-diphosphate geranylgeranyltransferase
trans-Pentaprenyltranstransferase
Tryptophan dimethylallyltransferase
Aspulvinone dimethylallyltransferase
Trihydroxypterocarpan dimethylallyltransferase
Leukotriene-C4 synthase
Isonocardicin synthase
4-Hydroxybenzoate nonaprenyltransferase
Aristolochene synthase
Phosphoglycerol geranylgeranyltransferase
Geranylgeranylglycerol-phosphate geranylgeranyltransferase
Aspartate transaminase
Alanine transaminase
Cysteine transaminase
Glycine transaminase
Tyrosine transaminase
Leucine transaminase
Kynurenine-oxoglutarate transaminase
2,5-Diaminovalerate transaminase
Histidinol-phosphate transaminase
Acetylornithine transaminase
Alanine-oxo-acid transaminase
Ornithine-oxo-acid transaminase
Asparagine-oxo-acid transaminase
Glutamine-pyruvate transaminase
Glutamine-fructose-6-phosphate transaminase (isomerizing)
Succinyldiaminopimelate transaminase
beta-Alanine-pyruvate transaminase
4-Aminobutyrate transaminase
D-Alanine transaminase
(S)-3-Amino-2-methylpropionate transaminase
4-Hydroxyglutamate transaminase
Diiodotyrosine transaminase
Thyroid-hormone transaminase
Tryptophan transaminase
Tryptophan-phenylpyruvate transaminase
Diamine transaminase
Pyridoxamine-pyruvate transaminase
Pyridoxamine-oxaloacetate transaminase
Valine-3-methyl-2-oxovalerate transaminase
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase
UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase
Glycine-oxaloacetate transaminase
L-Lysine 6-transaminase
(2-Aminoethyl)phosphonate-pyruvate transaminase
Histidine transaminase
2-Aminoadipate transaminase
(R)-3-Amino-2-methylpropionate-pyruvate transaminase
D-Methionine-pyruvate transaminase
Branched-chain-amino-acid transaminase
Aminolevulinate transaminase
Alanine-glyoxylate transaminase
Serine-glyoxylate transaminase
Diaminobutyrate-pyruvate transaminase
Alanine-oxomalonate transaminase
5-Aminovalerate transaminase
Dihydroxyphenylalanine transaminase
Glutamine-scyllo-inosose transaminase
Serine-pyruvate transaminase
Phosphoserine transaminase
Pyridoxamine-phosphate transaminase
Taurine transaminase
1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase
Aromatic-amino-acid transaminase
Phenylalanine(histidine) transaminase
dTDP-4-amino-4,6-dideoxygalactose transaminase
Aromatic-amino-acid-glyoxylate transaminase
(R)-3-Amino-2-methylpropionate transaminase
Adenosylmethionine-8-amino-7-oxononanoate transaminase
Kynurenine-glyoxylate transaminase
Glutamine-phenylpyruvate transaminase
N6-Acetyl-beta-lysine transaminase
Valine-pyruvate transaminase
2-Aminohexanoate transaminase
Ornithine(lysine) transaminase
N2-Acetylornithine 5-transaminase
Aspartate-phenylpyruvate transaminase
Lysine-pyruvate 6-transaminase
D-4-Hydroxyphenylglycine transaminase
Methionine-glyoxylate transaminase
Cephalosporin-C transaminase
Cysteine-conjugate transaminase
Oximinotransferase
dATP(dGTP)-DNA purinetransferase
Hexokinase
Glucokinase
Ketohexokinase
Fructokinase
Rhamnulokinase
Galactokinase
Mannokinase
Glucosamine kinase
Phosphoglucokinase
6-Phosphofructokinase
Gluconokinase
Dehydrogluconokinase
Sedoheptulokinase
Ribokinase
Ribulokinase
Xylulokinase
Phosphoribokinase
Phosphoribulokinase
Adenosine kinase
Thymidine kinase
Ribosylnicotinamide kinase
NAD+ kinase
Dephospho-CoA kinase
Adenylylsulfate kinase
Riboflavin kinase
Erythritol kinase
Triokinase
Glycerone kinase
Glycerol kinase
Glycerate kinase
Choline kinase
Pantothenate kinase
Pantetheine kinase
Pyridoxal kinase
Mevalonate kinase
Protein kinase
Phosphorylase kinase
Homoserine kinase
Pyruvate kinase
Glucose-1-phosphate phosphodismutase
Riboflavin phosphotransferase
Glucuronokinase
Galacturonokinase
2-Dehydro-3-deoxygluconokinase
L-Arabinokinase
D-Ribulokinase
Uridine kinase
Hydroxymethylpyrimidine kinase
Hydroxyethylthiazole kinase
L-Fuculokinase
Fucokinase
L-Xylulokinase
D-Arabinokinase
Allose kinase
1-Phosphofructokinase
2-Dehydro-3-deoxygalactonokinase
N-Acetylglucosamine kinase
N-Acylmannosamine kinase
Acyl-phosphate-hexose phosphotransferase
Phosphoramidate-hexose phosphotransferase
Polyphosphate-glucose phosphotransferase
myo-Inositol 1-kinase
scyllo-Inosamine 4-kinase
Undecaprenol kinase
1-Phosphatidylinositol 4-kinase
1-Phosphatidylinositol-4-phosphate 5-kinase
Protein-Npi-phosphohistidine-sugar phosphotransferase
Protamine kinase
Shikimate kinase
Streptomycin 6-kinase
Inosine kinase
Deoxycytidine kinase
Deoxyadenosine kinase
Nucleoside phosphotransferase
Polynucleotide 5'-hydroxyl-kinase
Pyrophosphate-glycerol phosphotransferase
Pyrophosphate-serine phosphotransferase
Hydroxylysine kinase
Ethanolamine kinase
Pseudouridine kinase
Alkylglycerone kinase
beta-Glucoside kinase
NADH kinase
Streptomycin 3"-kinase
Dihydrostreptomycin-6-phosphate 3'alpha-kinase
Thiamine kinase
Pyrophosphate-fructose-6-phosphate 1-phosphotransferase
Sphinganine kinase
5-Dehydro-2-deoxygluconokinase
Alkylglycerol kinase
Acylglycerol kinase
Kanamycin kinase
[Pyruvate dehydrogenase (lipoamide)] kinase
5-Methylthioribose kinase
Tagatose kinase
Hamamelose kinase
Viomycin kinase
Pyrophosphate-protein phosphotransferase.