Fast Facts: Comprehensive Genomic Profiling
Making precision medicine possible
E-Book
Fast Facts: Comprehensive Genomic Profiling
Making precision medicine possible
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: Genetic mutations and biomarkers Understanding next-generation sequencing Elements of comprehensive genomic profiles Role in precision oncology Predictive and prognostic biomarkers Overcoming barriers to genotype-directed therapy
Rapoport, Bernardo L.
Troncone, Giancarlo
Schmitt, Fernando
Nayler, Simon
| ISBN | 9783318068191 |
|---|---|
| Artikelnummer | 9783318068191 |
| Medientyp | E-Book - ePUB |
| Copyrightjahr | 2020 |
| Verlag | Karger |
| Umfang | 108 Seiten |
| Sprache | Englisch |
| Kopierschutz | Adobe DRM |
