Ferroptosis: Mechanism and Diseases
Ferroptosis: Mechanism and Diseases
This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron metabolism and its connection to ferritinophagy, a ferritin selective autophagy, with profound implications in neurodegenerative diseases such as Alzheimer, Parkinson, Huntington and ALS. Lastly, it describes necroptosis, another important form of cell death, along with its connections to human disorders and potential crosstalk with ferroptosis.
While covering basic concepts, the book delvesinto mechanisms and modulation of ferroptosis for treating a wide variety of human diseases thus offering a valuable and informative resource for both, scientists and clinical researchers.
Foreword
Ferroptosis: Concepts and DefinitionsOvercoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT inhibitors
Iron Homeostasis and Metabolism: Two Sides of a Coin
The Role of NCOA4-mediated Ferritinophagy in Ferroptosis
Emerging Role for Ferroptosis in Infectious Diseases
Small Molecule Regulators of Ferroptosis
Necroptosis, The other main Caspase-Independent Cell Death.
Florez, Andrés F.
Alborzinia, Hamed
| ISBN | 978-3-030-62025-7 |
|---|---|
| Artikelnummer | 9783030620257 |
| Medientyp | Buch |
| Auflage | 1st ed. 2021 |
| Copyrightjahr | 2021 |
| Verlag | Springer, Berlin |
| Umfang | IX, 140 Seiten |
| Abbildungen | IX, 140 p. 37 illus., 33 illus. in color. |
| Sprache | Englisch |
