This book summarizes evidence on frailty and ageing, how this may impact patient outcomes and how frailty can be assessed, managed and incorporated in the decision-making process for older patients with cancer.  The book aims to:  empower clinical teams to assess and support older cancer patients with frailty, ideally within a multidisciplinary setting; and to improve the selection of older cancer patients to the most appropriate management/treatment strategies in order to improve the outcomes of this group of patients often underrepresented in research. 

The reader will learn the methods available for assessing frailty, such as screening tools, but also how to perform different geriatric assessments covering the different key components (physical, nutritional, social, psychological, etc.). The book also provides information on how to manage and intervene on frailty with the role of pre-habilitation and re-habilitation, how to set-up specialised teams and pathways within one's hospital and community for these older cancer patients with frailty. Finally, the management of this challenging group of patients according to the cancer type is discussed in detail, alongside with mapping the unmet research needs and future directions in this field.

Introduction to frailty in older adults with cancer

Global action and policies in older adults with cancer and frailty
Frailty screening and comprehensive geriatric assessment
Cognitive impairment in older adults with cancer and frailty
Psychosocial dimension in older adults with cancer and frailty
Comorbidity and polypharmacy in older adults with cancer and frailty
Malnutrition, cachexia and sarcopenia in older adults with cancer and frailty
Physical performance and functional status in older adults with cancer and frailty
Prehabilitation and rehabilitation in older adults with cancer and frailty
Holistic needs assessment and advance care planning in older adults with cancer and frailty
Multidisciplinary onco-geriatric care models
Decision-making process in older adults with cancer and frailty
Perioperative care in older adults with cancer and frailty
Radiotherapy and systemic anti-cancer treatment in older adults with cancer and frailty
Palliative carein older adults with cancer and frailty
Frailty research: the present and the future
Breast cancer in older adults with frailty
Non-small cell lung cancer in older adults with frailty
Colorectal cancer in older adults with frailty
Prostate cancer in older adults with frailty
Renal cell carcinoma in older adults with frailty
Cutaneous melanoma in older adults with frailty
Gastroesophageal cancer in older adults with frailty
Hepatopancreaticobiliary cancer in older adults with frailty
Gynaecological cancer in older adults with frailty
Head and neck cancer in older adults with frailty
Hematological cancer in older adults with frailty.