This publication of a symposium held on 24 th and 25 th of June 1988 in Munich th is dedicated to Nepomuk Zollner on the occasion of his 65 birthday, expressing the best wishes of the authors. Nepomuk Zollner was born in the northern part of Bavaria. While a medical student in Munich he was called up to military duty in the last year of World War II. After achieving excellent results on his examinations he served as a physician in several hospitals in Munich and soon became interested in inborn errors of metabolism. In order to receive the best education possible at that time he joined the group of S. J. Thannhauser, the famous German emigrant, in Boston where he worked from 1951 to 1953. There he was able to continue his studies on lipids, which he had started in 1948, and begin with his studies on purine metabolism. While working in Thannhauser's laboratory he learned to think and act according to the strict laws of natural SCIence. After returning to Europe he concentrated his scientific work on purines and lipids. Gout and hyperlipoproteinemias from the genetic to the therapeutic aspects remained the dominating topics of his research activities. In spite of many obligations as head of the Medical Polyclinic of the University of Munich and many activities at the university and in scientific societies Zollner's foremost intent continued to be the development and progress of natural science in medicine.

Genetic Aspects: Lipid Metabolism

DNA Polymorphisms in the Diagnosis of Familial Hypercholesterolaemia
Molekularbiologie und klinische Forschung: das Beispiel des LDL-Rezeptors und der Familiären Hypercholesterinämie
Genetics, Drugs and Low Density Lipoprotein Metabolism
Visualization and Characterization of the Scavenger Receptor in Human Liver
Expression of Human Apo AI, AII and CII Genes in Pro- and Eukaryotic Cells
Genetic Aspects : Purine Metabolism
Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency: Molecular Basis and Clinical Relevance
Molecular Basis of AMP Deaminase Isoform Diversity
Purine Excretion
Nephrolithiasis in the Context of Purine Metabolism
Therapeutic Aspects: Hyperlipidemia
Prognosis of Dyslipoproteinemia
Acute and Chronic Effects of Diet and Physical Exercise on Plasma Lipids
Present Concepts for Drug Treatment of Hyperlipidaemia in Adults
Comparison of Different Forms of Plasmapheresis
Extracorporeal Plasma Therapy in the Treatment of Severe Hyper-?-Lipoproteinemia: The HELP System
LDL Apheresis: 7 Years of Clinical Experience
Therapeutic Aspects: Disturbances of Purine Metabolism
Clinical Aspects of Gout
Diet und Drug Treatment of Gout
The Development of Antiviral Compounds Against HIV and Herpesviruses.