Glycans in Diseases and Therapeutics

Glycans in Diseases and Therapeutics

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Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.

This volume of the series "Biology of Extracellular Matrix" reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.



Heparan Sulfate Proteoglycan in Inflammation and Angiogenesis
Heparan Sulfate Proteoglycans in Infection
Glycans in cancer
Glycosaminoglycans in atherosclerosis and thrombosis
Glycans in Embryonic Stem Cells
Heparan sulfate proteoglycans in cancer progression and therapy
Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?.
ISBN 978-3-642-16832-1
Artikelnummer 9783642168321
Medientyp Buch
Auflage 2011
Copyrightjahr 2011
Verlag Springer, Berlin
Umfang XII, 188 Seiten
Abbildungen XII, 188 p.
Sprache Englisch