The synthesis of very complex saccharide structures is one of the most challenging areas of modern glycoscience. This volume presents the state of the art of complex carbohydrate synthesis, written by leading scientists whose groups are making major contributions in the field. Reflecting the particular interest in inhibitors and modulators as well as in mimetics, an in-cepth treatment is given both of their selective syntheses and of their biological implications. In addition the concept of multivalent glycoconjugate recognition as well as supramolecular implications of amphiphilic carbohydrates are highlighted.

Nucleophilic C-glycosyl donors for C-glycoside synthesis

Synthesis of C-glycosides of biological interest
Thiooligosaccharides in glycobiology
Aldonolactones as chiral synthons
Chemical and chemo-enzymatic approaches to glycosidase inhibitors with basic nitrogen in the sugar ring
The synthesis of novel enzyme inhibitors and their use in defining the active sites of glycan hydrolases
Heparinoid mimetics
Recent developments in the rational design of multivalent glycoconjugates
Amphiphilk carbohydrates as a tool for molecular recognition in organized systems.