HIV-1 Latency
E-Book
HIV-1 Latency
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
Guido Silvestri
Emory University School of Medicine, Atlanta, GA 30329, USA
gsilves@emory.edu
Mathias Lichterfeld
The Brigham and Women's Hospital and the Ragon Institute of MGH, MIT and Harvard, Boston, MA, USA
MLICHTERFELD@mgh.harvard.edu
Silvestri, Guido
Lichterfeld, Mathias
| ISBN | 9783030028169 |
|---|---|
| Artikelnummer | 9783030028169 |
| Medientyp | E-Book - PDF |
| Copyrightjahr | 2018 |
| Verlag | Springer-Verlag |
| Umfang | 248 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
