HIV-1 Latency
HIV-1 Latency
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
<p>Molecular Control of HIV and SIV Latency
Assays to Measure Latency, Reservoirs and ReactivationThe Antiviral Immune Response and its Impact on the HIV-1 Reservoir
Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiretroviral Therapy
SIV Latency in Macrophages in the CNS
Mathematical models of HIV latency
Residual Immune Activation and Latency
Immune Interventions to Eliminate the HIV Reservoir
Cell and Gene Therapy for HIV Cure.</p><br>
Silvestri, Guido
Lichterfeld, Mathias
| ISBN | 978-3-030-13214-9 |
|---|---|
| Artikelnummer | 9783030132149 |
| Medientyp | Buch |
| Auflage | Softcover reprint of the original 1st ed. 2018 |
| Copyrightjahr | 2019 |
| Verlag | Springer, Berlin |
| Umfang | VII, 248 Seiten |
| Abbildungen | VII, 248 p. |
| Sprache | Englisch |
