Globally, HIV-associated tuberculosis is one of the most important causes of infection-related death, accounting for one in every three HIV deaths and over 300,000 in 2017 alone. The HIV epidemic has undermined tuberculosis-control efforts in many countries around the world, as the virus has important modifying effects on the pathogenesis, diagnosis, and treatment of TB. The management of HIV-associated TB is also complicated by rapid clinical progression, immune reconstitution inflammatory syndrome, drug-drug interactions, and shared toxicities.

1.Overview of the HIV-associated tuberculosis epidemicContance A. Benson<br>2.Epidemiology of Drug-susceptible, Drug-resistant Tuberculosis and HIV in AfricaKogieleum Naidoo and Nikita Naicker<br>3.Modelling the HIV-associated TB epidemic and the impact of interventions aimed at epidemic controlP.J. Dodd, C. Pretorius, B.G. Williams<br>4.Immune Responses to Mycobacterium tuberculosis and the impact of HIV infectionCatherine Riou, Cari Stek, Elsa Du Bruyn<br>5.Clinical Manifestations of HIV-associated tuberculosis in adultsSean Wasserman, David Barr, Graeme Meintjes<br>6.The tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS)Irini Sereti, Gregory P. Bisson, Graeme Meintjes<br>7.Diagnosis of HIV-associated tuberculosisAndrew Kerkhoff, Adithya Cattamanchi<br>8.Recent advances in the treatment of latent tuberculosis infection among adults living with HIV infectionApril C. Pettit, Timothy R. Sterling<br>9.Treatment of drug-sensitive tuberculosis in persons with HIVAlice K. Pau, Safia Kuriakose, Kelly E. Dooley, Gary Maartens<br>10.Drug-resistant TB and HIVSara C. Auld, Neel R. Gandhi, James C.M. Brust<br>11.Co-treatment of tuberculosis and HIV: pharmacologic considerationsEthel D. Weld, Alice K. Pau, Kelly E. Dooley<br>12.HIV and TB in childrenTonya Arscott-Mills, Ben Marais, Andrew Steenhoff<br>13.Neurological TB in HIVLouise Bovijn, Regan Solomons, Suzaan Marais<br>