Handbook of Chemical Glycosylation

Advances in Stereoselectivity and Therapeutic Relevance

Handbook of Chemical Glycosylation

Advances in Stereoselectivity and Therapeutic Relevance

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Since carbohydrate oligomers are still a challenge in synthetic chemistry, this book on recent developments fulfils a great need. Covering the chemistry necessary to synthesize exact copies of these structures, top authors from all around the world comprehensively deal with synthesis from anomeric halides, from miscellaneous glycosyl donors, and by indirect and special methods, as well as 1-oxygen-and 1-sulfur-substituted derivatives. They demonstrate the best approach for the stereoselective formation of the intermonomeric bond, making this essential reading for every biochemist working in biosynthesis, the exploration of biopathways and vaccines.

GENERAL ASPECTS OF THE GLYCOSIDIC BOND FORMATION<br>GLYCOSIDE SYNTHESIS FROM ANOMERIC HALIDES<br>Glycosyl Fluorides<br>Glycosyl Chlorides, Bromides, and Iodides<br>GLYCOSIDE SYNTHESIS FROM 1-OXYGEN-SUBSTITUTED GLYCOSYL DONORS<br>Hemiacetals and O-Acyl/Carbonyl Derivatives<br>Glycosyl Imidates<br>Anomeric Transglycosylation<br>Phosphites, Phosphates, and Other O--P Derivatives<br>GLYCOSIDE SYNTHESIS FROM 1-SULFUR/SELENIUM-SUBSTITUTED DERIVATIVES<br>Thioalkyl and Thioaryl Glycosides<br>Sulfoxides, Sulfimides, and Sulfones<br>Xanthates, Thioimidates, and Other Thio Derivatives<br>Selenoglycosides<br>OTHER METHODS FOR GLYCOSIDE SYNTHESIS <br>Orthoesters and Related Derivatives<br>Dehydro and Anhydro Derivatives<br>Miscellaneous Glycosyl Donors<br>Indirect and Special Methods<br>
ISBN 9783527317806
Artikelnummer 9783527317806
Medientyp Buch
Auflage 1. Auflage
Copyrightjahr 2008
Verlag Wiley-VCH
Umfang XXII, 502 Seiten
Abbildungen 492 SW-Abb., 14 Tabellen
Sprache Englisch