Irritant dermatitis is a common condition, accounting for a significant proportion of occupational skin disease. The recent advent of non-invasive skin bioengineering technology has accelerated dermatology research in this field. This book provides a comprehensive reference text on irritant contact dermatitis, covering all aspects of the condition, including: clinical features, epidemiology, prevention and therapy, prognosis, mechanisms, pathology and regulatory issues. The book also presents novel in vitro and in vivo research techniques and findings. As irritant dermatitis affects multiple specialties, the audience for this book is wide ranging, including clinical and investigative dermatologists, allergists, toxicologists, pharmaceutical scientists, occupational and environmental physicians, public health physicians, cosmetologists and skin bioengineers.

A Classification and clinical features: Ten Genotypes of Irritant Dermatitis

Irritant versus Allergic Dermatitis
B Special clinical forms: Barrier Function and Perturbation: Relevance for Interdigital Dermatitis
Friction Melanosis
Diaper Dermatitis
Chemical Skin Burns
Contact Urticaria
Airborne Irritant Dermatitis
Irritant Dermatitis of the Scalp
Irritant Dermatitis of the Nails
C Epidemiology: Epidemiology of Irritant Dermatitis
Epidemiology of Irritant Dermatitis in the Tropics
D Occupational irritant dermatitis: Occupational Issues of Irritant Dermatitis
Hairdressing
Metalworkers
Health Care Workers
The Electronics Industry
Painters Lacquerers& Varnishers
E. Risk factors for irritant dermatitis: Age
Gender
Ethnicity
Atopy
F Insights from bioengineering; Prediction Bioengineering
Quantitative Sonography for the Evaluation of Irritant Reactions
Functional Skin Testing: the SMART procedures
Bioengineering Correlates of the Sensitive Skin Syndrome: The Sensory Irritation Component
Squamometry
G The Irritants: special issues: Corrosive Materials
Detergents
Sodium Lauryl Sulfate (SLS)
Organic Solvents
Oils Cutting Fluids Lubricants
Food
Dithranol
Copper
Fatty Acid Binding Proteins
H Mechanisms of irritant dermatitis: Histopathology of Irritant Contact Dermatitis
Percutaneous Absorption and Irritant Dermatitis
Cytokines
Oxidative Stress
Langerhans Cells and Irritant Dermatitis
Hydration Injury
I Prevention of Irritant dermatitis: Primary Prevention of Irritant Contact Dermatitis
Protective Gloves
Anti-Irritants
Barrier Creams
Moisturizers and Irritant Contact Dermatitis (1)
Moisturizers and Irritant Contact Dermatitis (2)
Effects of CO2 on Barrier Recovery
J Management and therapy: The Treatment of Irritant Dermatitis
Topical Corticosteroids in the Treatment of Irritant Dermatitis
Barrier Creams and Emollients
K Product testing: In Vivo Models of Skin Irritation
In Vitro Methods to Predict Skin Irritation
M Appendices: I.Questionnaire Methods for Contact Dermatitis Patients
II. Patient Information Sheets
Hand Protection for Hand Dermatitis
Overnight Plastic Occlusion for Hand Dermatitis
Hand Dermatitis Treatment
III.Selected Sources of Information for Irritant Contact Dermatitis.