This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.

History of Pediatric BMT

Stem Cell Sources and Donor Selection .-Preparative Regimens.-Graft-versus-Host Disease.-Complications Following BMT an Supportive Care.-Late Effects.-Acute Lymphoblastic Leukemia.-Acute Myeloid Leukemia.-Lymphomas.-Myelodysplastic and Myeloproliferative Disorders.-Solid Tumors.-Non-Malignant Diseases.-Future Directions.