A must-read handbook on heterocycle chemistry with a focus on sustainability

Heterocycles feature prominently in our daily life-they are essential for pharmaceuticals, agrochemicals, and fine chemicals. More, numerous natural, bioactive products contain heterocyclic compounds. As a result, heterocyclic chemistry continues to be one of the most important areas of study in organic chemistry.

Heterocycles provides an important reference on a wide range of topics relating to heterocyclic chemistry, with a heavy emphasis on sustainable methods and greener syntheses. The book describes state-of-the-art synthetic methods, such as photochemical reactions, dearomatization reactions, organocatalysis, transition metal catalysis, and biocatalysis. It also covers:

• Sustainable methods, like flow chemistry, mechanochemistry, and multicomponent synthesis
• Strategies for the synthesis of heterocyclic macrocycles and medium-sized rings
• Characterization of heterocyclic compounds

Heterocycles is a useful reference for organic chemists, natural products chemists, catalytic chemists, and medicinal chemists in academia and industry.

Teresa M.V.D. Pinho e Melo is an Associate Professor at the University of Coimbra, Portugal. She is Head of the Organic Chemistry Research Group of the Coimbra Chemistry Centre and her research interests are in the area of synthetic and mechanistic heterocyclic chemistry as well as medicinal chemistry.

Marta Pineiro is an Assistant Professor at the University of Coimbra, Portugal. Her research interests are in the area of sustainable organic synthesis, microwave-assisted organic synthesis, mechanochemistry, and synthesis and applications of heterocycles with unique photophysical properties.