This book covers topics that range from fundamental studies of DNA replication, chromosomal and nuclear function through growth factor control of endocrine tumor initiation and progression. The basic and translational insights gained from Hormonal Control of Cell Cycle will be of interest to those studying the biology of endocrine tumors as well as those deriving novel therapeutic approaches for these benign and malignant disorders.
1;Preface;5 2;Table of Contents;6 3;List of Contributors;7 4;DNA Replication Origins, Development, and Cancer;11 5;Getting In and Out of Mitosis;21 6;Nuclear Receptors and Cyclins in Hormone Signaling;31 7;A Novel Function for Cyclin E in Cell Cycle Progression;41 8;IGF-I and the Regulation of Cell Cycle Progression in Smooth Muscle Cells;50 9;Deciphering the Conundrum of Estrogen-driven Breast Cancer: Aurora Kinase Deregulation;58 10;Androgen-mediated Control of the Cyclin D1-RB Axis: Implications for Prostate Cancer;72 11;Pituitary Trophic Status as a Tumorigenic Determinant;91 12;p27 Regulation by Estrogen and Src Signaling in Human Breast Cancer;96 13;The Synergy of Two Ovarian Hormone-induced Enzymes in Human Mammary Carcinogenesis;105 14;Steroid Receptors, Stem Cells and Proliferation in the Human Breast;116 15;Estrogens, Cell Proliferation and Breast Cancer;127 16;Subject Index;143
Melmed, Shlomo
Rochefort, Henri
Chanson, Philippe
Christen, Yves
| ISBN | 9783540738558 |
|---|---|
| Artikelnummer | 9783540738558 |
| Medientyp | E-Book - PDF |
| Copyrightjahr | 2007 |
| Verlag | Springer-Verlag |
| Umfang | 145 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
