This book is a compilation of scientific papers presented at the Seventh Interna tional Symposium on Intracranial Pressure and Brain Injury, held in Ann Arbor, Michigan, USA, June 20-23, 1988. The symposium explored both clinical and basic science aspects of intracranial pressure dynamics and their clinical applica tion. Neuroscientists including neurologists, neurosurgeons, neuroanesthesiolo gists, neuroradiologists, neurochemists, biophysicists and physiologists contrib uted to the state-of-the-art presentations and discussions. Open exchange of ideas characterized this meeting as it did the initial meeting in Hanover, Germany in 1972 and subsequently at tri-annual meetings in Lund, Sweden; Groningen, Holland; Williamsburg, Virginia; Tokyo, Japan; and Glas gow, Scotland. The next Intracranial Pressure Symposium, to be held in Rotter dam, Holland, in 1991, will continue this tradition. The papers in this book have been grouped for the reader's convenience. Clinical and basic science papers focus on the same subject, consequently they appear together. Subjects include monitoring; biophysics; CSF dynamics and hydrocephalus; control of intracranial pressure; trauma, hemorrhage, and in flammation; free radicals; cerebral perfusion and metabolism; and brain edema. The science of intracranial pressure and its relevance to human illness con tinues to provide fascination for investigators throughout the world. This book reflects the research of many of them and, hopefully, will stimulate new and innovative inquiries.

Session I: Monitoring

Measuring ICP in Patients - Its Value Now and in the Future?
Physical Characteristics of Various Methods for Measuring ICP
An Approach to Noninvasive Analysis of Intracranial Pressure (ICP) Using an Ultrasonic Probe
Clinical Evaluation of the Catheter Tipped Camino Transducer Inserted via a Subdural Screw
Clinical and Laboratory Evaluation of the Camino Intracranial Pressure Monitoring System
Clinical Experience with a Fiber Optic Brain Parenchymal Pressure Monitor
Test of a Non-invasive PVI Measure with a Fiber-optic Pressure Monitoring Device in Head Injured Patients
Differential Intracranial Pressure Recordings in Patients with Dual Ipsilateral Monitors
A New Fiberoptic Monitoring Device: Development of the Ventricular Bolt
Development of a Fully Implantable Epidural Pressure (EDP) Sensor
Evaluation of a Fibre-optic System for Monitoring Ventricular Pressure
Clinical Evaluation of a Fiberoptic Device for Measuring PVI
Microprocessor-driven ICP Fiber Optic Monitor
Microprocessor-driven ICP Monitor: Instrumentation
Comparison of Intracranial Pressure Transducers
Intraparenchymal Brain Pressure - Clinical Evaluation
Lumbar Pressure Monitoring with a New Fiberoptic Catheter
Evaluation of Continuous Lumbar Subarachnoid Pressure Monitoring
Intracranial Pressure Monitoring After Elective Surgery: A Study of 514 Consecutive Patients
Intracranial Compliance Monitoring with Computerized ICP Waveform Analysis in 55 Comatose Patients
Software for Neurosurgery Intensive Care
The Best Dichotomous Parameters for Predicting Mortality and a Good Outcome Following 48 Hours of ICP Monitoring
Non-invasive Monitoring of ICP in Infants
The Human Factor in the Accuracy of Intracranial Pressure (ICP) Monitoring Using Extradurally Placed Microtransducers
Rate of Infection and Cost Containment in Intracranial Pressure Recording
Continuous Monitoring of Middle Cerebral Arterial Blood Velocity and Cerebral Perfusion Pressure
Analysis of Frequency Spectrum of the Intracranial Pulse Wave in Cerebral Vasospasm
Intracranial Volume and Pressure Load Tolerance Evaluated by Continuous Measurement of Doppler Flow Velocity in Intracranial Vessels in Cats
Simultaneous Monitoring of ICP and Transcranial Doppler Sonogram on the Middle Cerebral Artery
Effect of Jugular Bulb Catheterization on Intracranial Pressure
Jugular Bulb Catheterization in Children
Transcardiac Method of Jugular Bulb Catheterization
Dynamic Pressure Volume Index via ICP Waveform Analysis
Single Pulse Pressure Wave Analysis by Fast Fourier Transformation
A Minicomputer System for Analysis and Display of ICP Related Data
Modified Auditory Brainstem Responses (MABR) in Patients with Intracranial Lesions
Detection of the Site of V-P Shunt Malfunction Using a Telemetric IVP Sensor
Relatiomship of Intracranial Pressure Changes to CT Changes in Children
Noninvasive Measurement of Intracranial Pressure (ICP) as a Screening Method for Evaluation of Hydrocephalus in Newborn and Infants
Correlations Between CT Features and ICP in Patients with Intracranial Lesions
EEG Spectrum Changes After the Bolus Injection of Thiopental
Session II: Biophysics Session
Can Waveform Analysis of ICP Separate Vascular from Non-Vascular Causes on Intracranial Hypertension?
The Origin of CSF Pulse Waves
Significance of Cortical Venous Pulse Pressure and Superior Sagittal Sinus Pulse Pressure on ICP-Pulse Pressure
Mathematical Modelling of the Contribution of Arterial Volumetric Pulsation to the Intracranial Pulse Wave
Single Pulse Spectral Analysis of Intracranial Pressures
Fourier Analysis of Intracranial Pressures During Experimental Intracranial Hypertension
Analysis of the Power Spectrum of the Pulse Pressure Wave During Induced Intracranial Hypertension in Humans
CSF Pulse Waves in a Model of Progressive Hydrocephalus: An Effect Not a Cause of Ventricular Enlargement
Normal Pressure Hydrocep