1;Preface;5 2;Contents;6 3;List of Contributors;20 4;1 Ten Genotypes of Irritant Contact Dermatitis;25 4.1;1.1 Introduction;25 4.2;1.2 Clinical Classification of Irritant Contact Dermatitis;25 4.3;References;29 5;2 Irritant Contact Dermatitis Versus Allergic Contact Dermatitis;30 5.1;2.1 Introduction;30 5.2;2.2 Clinical Aspects;30 5.3;2.3 Histology and Immunohistochemistry;31 5.4;2.4 Pathogenetic Mechanisms;33 5.5;2.5 Conclusions;35 5.6;References;35 6;3 Barrier Function and Perturbation: Relevance for Interdigital Dermatitis;39 6.1;3.1 Introduction;39 6.2;3.2 Lamellar Body Secretion;39 6.3;3.3 Stratum Corneum Lipids;40 6.4;3.4 The Autonomous Stratum Corneum;41 6.5;3.5 Synthetic Activities to Barrier Function;41 6.6;3.6 Regional Variations in Skin Permeability;42 6.7;3.7 Irritant Contact Dermatitis;42 6.8;3.8 Interdigital Dermatitis - A Form of Irritant Contact Dermatitis;43 6.9;References;44 7;4 Friction Melanosis;47 7.1;4.1 Introduction;47 7.2;4.2 The Feature and Cause of Friction Melanosis;47 7.3;4.3 Comment;47 7.4;References;51 8;5 Diaper Dermatitis;52 8.1;5.1 Introduction;52 8.2;5.2 Birth;53 8.3;5.3 Factors Influencing Diaper Dermatitis;56 8.4;5.4 Effect of Diaper Type and Composition;60 8.5;5.5 Diapers for Delivery of Topical Preparations;63 8.6;5.6 Effect of Diaper Occlusion;64 8.7;6 Summary;64 8.8;References;65 9;6 Chemical Skin Burns;67 9.1;6.1 Introduction;67 9.2;6.2 Definition;67 9.3;6.3 Diagnosis;70 9.4;6.4 Clinical Features;70 9.5;6.5 Treatment;71 9.6;6.6 Complications;72 9.7;6.7 Prevention;73 9.8;6.8 Summary;73 9.9;References;74 10;7 Contact Urticaria Syndrome;76 10.1;7.1 Introduction;76 10.2;7.2 Epidemiology;76 10.3;7.3 Mechanisms of Contact Urticaria;76 10.4;7.4 Symptoms and Signs;78 10.5;7.5 Site Specificity of Contact Urticaria Reactions;78 10.6;7.6 Human Experimental Protocols;78 10.7;7.7 Clinical Assessment and Quantitative Methods;80 10.8;7.8 Animal Experimental Protocols;81 10.9;7.9 Conclusion;81 10.10;References;82 11;8 Airborne Irritant Dermatitis;84 11.1;8.1 Introduction;84 11.2;8.2 Airborne Irritant Dermatitis Due to Fibers;84 11.3;8.3 Airborne Irritant Dermatitis Due to Dust Particles;87 11.4;8.4 Airborne Irritant Dermatitis Due to Sprays, Vapors, and Gases;89 11.5;8.5 Diagnostic Procedures: Tools Available to Investigate and Confirm ( or Refute) the Diagnosis of Airborne Irritant Dermatitis;91 11.6;References;91 12;9 Irritant Dermatitis of the Scalp;93 12.1;9.1 Introduction;93 12.2;9.2 Irritant Dermatitis of the Scalp Due to Mechanical Factors;93 12.3;9.3 Irritant Dermatitis of the Scalp Due to Chemical Agents;95 12.4;References;99 13;10 Irritant Contact Dermatitis of the Nails;101 13.1;10.1 Mechanical Irritation;101 13.2;10.2 Physical Agents;102 13.3;10.3 Chemical;102 13.4;10.4 Biological;104 13.5;10.5 Prevention and Therapy;104 13.6;References;104 14;11 Importance of Irritant Contact Dermatitis in Occupational Skin Disease1;107 14.1;11.1 Patients and Methods;107 14.2;11.2 Results;108 14.3;11.3 Discussion;108 14.4;11.4 Conclusions;112 14.5;References;112 15;12 Irritant Contact Dermatitis in the Tropics;114 15.1;12.1 Introduction;114 15.2;12.2 Epidemiology of Irritant Contact Dermatitis in the Tropics;114 15.3;12.3 Common Sources and Types of Contact Irritant Dermatitis in the Tropics;115 15.4;12.4 Conclusions;116 15.5;References;117 16;13 Occupational Issues of Irritant Contact Dermatitis;119 16.1;13.1 Introduction;119 16.2;13.2 Clinical Features and Classification;119 16.3;13.3 Epidemiology;120 16.4;13.4 Modulation of Occupational Irritant Contact Dermatitis;121 16.5;13.5 High-Risk Occupations and Irritants;122 16.6;13.6 Diagnosis;124 16.7;13.7 Management: Prevention and Therapy;125 16.8;References;126 17;14 Hairdressing;129 17.1;14.1 Occupational Tasks and Their Irritants;129 17.2;14.2 Epidemiology, Pattern, and Course of Irritant Contact Dermatitis;131 17.3;14.3 Risk Factors for Irritant Contact Dermatitis in Hairdressers;134 17.4;14.4 Prevention of ICD;135 17.5;References;139 18;15 Occupational