Irritant dermatitis is a common condition, accounting for a significant proportion of occupational skin disease. The recent advent of non-invasive skin bioengineering technology has accelerated dermatology research in this field. This book comprises an exhaustive reference text on irritant contact dermatitis, covering all aspects of the condition: clinical features, epidemiology, prevention and therapy, prognosis, mechanisms, pathology and regulatory issues. The book also presents novel in vitro and in vivo research techniques and findings. As irritant dermatitis affects multiple specialties, the audience for this book is wide, including clinical and investigative dermatologists, allergists, toxicologists, pharmaceutical scientists, occupational and environmental physicians, public health physicians, cosmetologists and skin bioengineers.

Classification and Clinical Features

Ten Genotypes of Irritant Contact Dermatitis
Irritant Contact Dermatitis ersus Allergic Contact Dermatitis
Special Clinical Forms
Barrier Function and Perturbation: Relevance for Interdigital Dermatitis
Friction Melanosis
Diaper Dermatitis
Chemical Skin Burns
Contact Urticaria Syndrome
Airborne Irritant Dermatitis
Irritant Dermatitis of the Scalp
rritant Contact Dermatitis of the Nails
Epidemiology
Importance of Irritant Contact Dermatitis in Occupational Skin Disease
Irritant Contact Dermatitis in the Tropics
Occupational Irritant Dermatitis
Occupational Issues of Irritant Contact Dermatitis
Hairdressing
Occupational Irritant Dermatitis - Metal Workers
Health Care Workers
The Electronics Industry
Painters, Lacquerers, and Varnishers
Risk Factors for Irritant Dermatitis
Age
Gender
Ethnicity
Atopy
Insights from Bioengineering
Prediction Bioengineering
Quantitative Sonography for the Evaluation of Irritant Reactions
Functional Skin Testing: the SMART Procedures
Bioengineering Correlates of the Sensitive Skin Syndrome: The Sensory Irritation Component
Squamometry
The Irritants: Special Issues
Corrosive Materials
Detergents
Sodium Lauryl Sulfate
Organic Solvents
Oils, Cutting Fluids, and Lubricants
Food
Dithranol
Copper
Fatty Acid Binding Proteins
Mechanisms of Irritant Dermatitis
Histopathology of Irritant Contact Dermatitis
Percutaneous Absorption and Irritant Dermatitis
Cytokines and Irritant Dermatitis
Oxidative Stress
Langerhans Cells and Skin Irritation
Hydration Injury
Prevention of Irritant Dermatitis
Primary Prevention of Irritant Contact Dermatitis
Protective Gloves
Anti-Irritants
Barrier Creams
Moisturizers.-Moisturizers and Irritant Contact Dermatitis (2)
Effects of CO2 on Barrier Recovery
Management and Therapy
Treatment of Irritant Contact Dermatitis
Topical Corticosteroids in the Treatment of Irritant Dermatitis
Barrier Creams and Emollients
Product Testing
In Vivo Models of Skin Irritation
In Vitro Methods to Predict Skin Irritation
Appendices
Questionnaire Methods for Hand Dermatitis Studies
Patient Information Sheets
Selected Sources of Information for Irritant Contact Dermatitis.