This book presents the latest insights into all the critical aspects of Klinefelter's Syndrome, in order to promote a more homogeneous a medical approach to this condition, leading to better and more "evidence-based" support, and improving patient satisfaction.

It offers physicians and all health professionals involved in treating these patients (andrologists, pediatricians, endocrinologists, psychologists) a comprehensive overview and a useful tool for their daily clinical practice.

Poetry

Preface
1. Introduction - From a disabling condition to a variant of normalcy
2. Epidemiology of an underdiagnosed syndrome
3. Causes of the extra chromosome/s
4. Different karyotypes, same disease?
5. Genetic and epigenetic aspects of the supernumerary X chromosome
6. Prenatal Counselling and management in the early neonatal period
7. Early developmental pathways and communication good practices
8. The diagnosis at prepubertal age
9. What to do and when from infancy to puberty
10. Neuropsychiatric aspects
11. Testicular development
12. The Klinefelter puberty
13. Genetic of Gametes
14. Phenotype of the adulthood
15. Hypothalamic-Pituitary Axis Function
16. The altered bone
17. Obesity, the rule or not
18. Lipids and glucose metabolism
19. Cardiovascular characteristics
20. The Thyroid Function
21. Oncological problems
22. Fertility preservation
23. Fertility vs Infertility
24. Psychological features
25.   Sexual function
26. Testosterone treatment in male patients with Klinefelter's syndrome.