his volume of the series Lecture Notes in Medical Informatics contains the T proceedings of the Workshop on System Engineering in Medicine, which was held in Maastricht, The Netherlands, 16-18 March 1989. This workshop was sponsored by the EC under the framework of the Medical and Health Research Programme. The aim of the workshop was to assess whether there was sufficient support in the Medical Informatics community in the EC to establish a concerted action. This proceedings contain papers of the presentations given at the workshop. These presentations were centred around three themes: - Methods and Tools - Applications in the domains of chronic care and critical care - Evaluation of decision support systems The papers were prepared after the workshop and therefore we were able to include the relevant parts of the discussions which were related to the presentations. As a result of the discussions during the workshop, a proposal was prepared for the establishment of a concerted action, specifically addressing the development of guidelines for the evaluation of medical decision aids. This proposal was granted early 1990 under the same Medical and Health Research programme of the EC. Over 40 institutes are participating in this concerted action. It have been the outstanding presentations and the open discussions at the workshop that have been the starting point of this concerted action. The papers in this proceedings formed a starting point for the discussions in the meetings of the concerted action.

Methods

The Use of the KADS Methodology in Designing an Intelligent Teaching System for Diagnosis in Physiotherapy
Machine Learning as a Tool for Knowledge Acquisition
Tools for Modeling Time-oriented Concepts: Applications for Retrieval of Liver Transplantation Data
Belief Network Representations of Temporal Knowledge for Medical Expert Systems
Decisions Based on Qualitative and Quantitative Reasoning
Knowledge Representation and Data Model to Support Medical Knowledge Base Transportability
Reliable and Reusable Tools for Medical Knowledge Based Systems
The MEDES Subshell: Towards an Open Architecture for Decision Support Systems
Applications: Management of the chronically ill
Evaluating Expert Critiques. Issues for the Development of Computer-Based Critiquing in Primary Care
Knowledge Acquisition for a Decision Support System for Anti-epileptic Drug Surveillance
DIACONS - Diabetes Consultant: Goals and Status
CARTES - A Prototype Decision Support System in Oncology
Applications: Management of the critically ill
Information Management and Decision Support for the Critically Ill
On Knowledge Based Systems in CCU's: Monitoring and Patients Follow-up
ARCA - An Integrated System for Cardiac Pathologies Diagnosis and Treatment
PC-based Multistep Infusion Regimens and On-line Control of Four Infusion Devices
A System for Interactive Knowledge-Based Simulation With Application in Management of the Critically Ill
Decision Support In Patient Monitoring By Interactive Information System Including Knowledge-Based Components
Computerized Monitoring And Decision Support During Anaesthesia
SIMPLEXYS Real Time Expert Systems in Patient Monitoring
Evaluation
The Evaluation of Medical Decision Support and Expert Systems:Reflections on the Literature
Evaluating Medical Expert Systems: What To Test, And How ?
The Role of Knowledge Based Systems in Medicine: Epistemological and Evaluation issues
Validity of Systems Application: User confidence in case application
Evaluation of Knowledge Based Systems from the User Perspective
Authors Index
List of Participants.