Molecular recognition undoubtedly governs any aspect of cellular interaction. To understand tumor cell growth regulation and spread, analysisof protein carbohydrate interactions can contribute to lead to the establishment of rational methods for diagnosis and therapy. Chemically and biochemically optimized preparation of adequate tools, their application for localization of receptor (tissue lectin) and ligand (cellular glycoconjugate) pairs in tumor cells and tumor sections and the usefulness of a lectin from a plant extract as potent immunomodulator indicate the prospect for a place of such techniques in pathology and oncology.

Molecular basis of lectin-carbohydrate interactions

Invertebrate lectins: new aspects in retrospects
Narcissus and Gerardia lectins: Tools for the development of a vaccine against AIDS and a new ELISA to quantify HIV-gp 120
Lectin histochemistry of human thyroid tumors
Neoglycoconjugates: Fundamentals and recent progresses
Neoglycoproteins and lectins in human lung cancer: A survey
How to localize ?-galactoside-specific endogenous lectins and their ligands in tissue sections: A comparison of the application of different histochemical tools in breast cancer
Endogenous receptors for carbohydrate ligands in human renal cell carcinoma
Brain, nerves and muscles: Neoglycoproteins in the practice of neuromorphology and neuropathology 123
Site-associated differences in endogenous lectin expression by mouse colon carcinoma cells
Differentiation-associated modulation of lactose- binding lectins in cancer cells
Change in metastasis and organotropism of mouse lymphoma variants associated with changes in expression of adhesion molecules and chemotactic responsiveness
Biomodulation: An integrated approach to access and manipulate biological information
Immunotherapeutic effects of purified mistletoe lectin (ML-I) on murine large cell lymphoma
The rationale of mitogenic lectin therapy for cancer
New perspectives in the treatment of acute myeloid leukemia by hematopoietic growth factors 229
Enzyme replacement therapy with macrophage-targeted human placental glucocerebrosidase in Gaucher disease
Preparation of neoglycoprotein-bearing liposomes and their interaction with cells and tissues
Membrane recognition of steroid-glycoprotein complexes: A model for steroid delivery to the target cells
Tumor cell-bone marrow stromal cell interaction:Neoglycoproteins as tools in leukemia research
Cell surface glycans influence the fate of circulating white blood cells
Fertilization: A model for cell-cell interaction
Endogenous mannose-binding lectins in brain development and function.