For the first time a compilation of chapters that depict the biological bases underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.

List of Contents

Molecular Biology of Lentivirus-Mediated Gene Transfer
HIV-1-Derived Lentiviral Vectors
Lentiviral Vectors Derived from Simian Immunodeficiency Virus
Nonprimate Lentiviral Vectors
Production of Lentiviral Vectors
Biosafety Issues in Lentivector Production
Lentiviral Vector Targeting
Integration Site Selection by Lentiviruses: Biology and Possible Control
Improving the Post-Transcriptional Aspects of Lentiviral Vectors
Lentiviruses as Vectors for CNS Diseases
Lentiviral Vectors for the Gene Therapy of Lympho-Hematological Disorders
Lentiviral Vectors for Gene Therapy of HIV-Induced Disease
Opportunities for the Use of Lentiviral Vectors in Human Gene Therapy.