A highly disabling infectious disease in developing countries, leprosy, or Hansen's disease, is caused by Mycobacterium leprae, and is still very relevant for the human community due to its transmissible nature, variable presentation and composite clinical picture. Early identification of leprosy and Buruli ulcer (also caused by a Mycobacterium, M. ulcerans) is critical to prevent spreading and patient disability and to establish appropriate therapy.

This richly illustrated, completely revised second edition of Leprosy and Buruli Ulcer describes the characteristic signs of both these diseases, and contents include abnormalities of the skin, nerves, eyes, hands, feet, testes and bone. It also presents the latest diagnostic tools to identify and quantify organ damage to enable readers to recognize and treat this composite systemic disorder, which can represent a true medical emergency if affecting eyes, nerves, and kidneys. Further, it includes additional chapters on leprosy in childhood, prophylaxis and vaccines. For both leprosy and Buruli ulcer, this handy guide helps practitioners and nursing personnel to spot the different clinical manifestations, make a prompt diagnosis and apply effective treatment of both these diseases.

Foreword

Preface
Part I Leprosy: General Section
1. History and Phylogeography of Leprosy
2.   Microbiology of Mycobacterium leprae
3. Genetics of Leprosy
4. Host Response to Mycobacterium leprae
5.   Pathogenesis of Leprosy
6. Classification of Leprosy
Part II Leprosy: Patient's Examination
7. Leprosy Patient History
8. Laboratory  Investigations in Leprosy
Part III Skin
9. Physical Examination in Leprosy: Skin
10. Clinical Features of Leprosy
11. Lucio-Latapí Leprosy
12. Histopathology of the Skin in Leprosy [FP1]
13.   Differential Diagnosis of Leprosy: Skin
Part IV  Leprosy and Nerves
14. Peripheral Nerves in Leprosy
15. The Leprosy Neuropathy
16. Primary Neural Leprosy
17. Chronic Neuropathic Pain in Leprosy
18. Electrodiagnostic Studies in Leprosy
19. Imaging in Leprosy
20. Differential Diagnosis of Leprosy: Nerves
Part V   Reactions in Leprosy.-21. Reactions in Leprosy
22. Lucio's Phenomenon in Leprosy
Part VI  Leprosy: Systemic Involvement
23. Ocular Involvement in Leprosy
24. Otolaryngological Manifestations of Leprosy
25.   Other Organs involved in Leprosy
Part VII Patient's Management in Leprosy
26. Diagnostic Work-Up of Leprosy
27. Drugs in Leprosy
28. Treatment and Prophylaxis of Leprosy
29. Prognosis of Leprosy
30.  Neurolysis in Leprosy
31. Prevention of Disability and Ulcer Care in Leprosy
32. Surgical and Social Rehabilitation in Leprosy
Part VIII   Leprosy and Community
33. Leprosy in Pregnancy
34. Leprosy in Childhood
35. Leprosy and HIV/AIDS Co-infection
36. Epidemiology  of  Leprosy
37. Leprosy Control
38. The Leprosy Mailing List
Part IX Buruli Ulcer: General Section
39. History and geographic distribution of Buruli ulcer
40. Microbiology of Mycobacterium ulcerans
Part X Buruli Ulcer: Patient's Examination
41. Laboratory Investigations in Buruli ulcer
42. Clinical Features of Buruli ulcer
43. Differential Diagnosis of Buruli ulcer
Part XI    Buruli Ulcer: Patient's Management
44. Diagnostic Work-up of Buruli ulcer
45.  Treatment of Buruli ulcer
46. Rehabilitation in Buruli ulcer
Part XII    Buruli Ulcer and Community
47. Epidemiology of Buruli ulcer
48. Buruli ulcer Control
Subject Index.