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This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease, placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation.

The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation.

This is an invaluable book  for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.



1. Anatomy and Embryology of the Liver

2. Liver Histology
3. Hepatic Progenitor Cells
4. Hepatocellular Death: Apoptosis, Autophagy, Necrosis and Necroptosis
5. Steatosis and inflammation in liver pathology
6. Molecular basis of fibrogenesis and angiogenesis during chronic liver disease: Impact of TGF-beta and VEGF on pathogenic pathways
7. Hepatotoxicity: Mechanisms of Liver Injury
8. Crosstalk of molecular signaling in hepatocellular carcinoma
9. Drug-Induced Liver Injury
10. Acquired Metabolic Disorders
11. Vascular Disorders of the Liver
12. Liver Ischaemia Reperfusion Injury
13. Autoimmune Hepatitis
14. Primary Sclerosing Cholangitis
15. Parasitic Diseases of the Liver
16. Viral Hepatitis B
17. Viral hepatitis C
18. Non-B, Non-C Viral Hepatitis
19. The Microbiome in Liver Diseases
20. Polycystic Liver Diseases
21. Portopulmonary Hypertension and Hepatopulmonary syndrome
22. HEPATIC ABSCESSES
23. Liver Cirrhosis
24. Primary BiliaryCholangitis
25. The Paucity of Interlobular Bile Ducts
26. Nonalcoholic Fatty Liver Disease: a wide spectrum disease
27. Alcoholic Liver Disease
28. Liver Disease in Pregnancy
29. Cirrhotic Cardiomyopathy
30. Benign Tumors
31. LIVER CANCER
32. Acute Liver Failure
33. Chronic Liver Failure and Acute-on-Chronic Liver Failure
34. History and Physical Examination
35. Assessment of Liver Function
36. Noninvasive Biomarkers for liver fibrosis
37. Peritoneal Fluid Analysis
38. Measurement of Hepatic Venous Pressure Gradient (HVPG)
39. Liver Biopsy for Histopathology
40. Abdominal Ultrasonography
41. Endoscopy in Hepatic Diseases
42. Dynamic and Multi-phase Contrast-enhanced CT Scan
43. Patient-specific 3D printing in Liver Disease
44. DYNAMIC CONTRAST-ENHANCED ULTRASONOGRAPHY OF THE LIVER
45. Ultrasound Elastography
46. MR Elastography and Functional MRI of the Liver
47. Dynamic Contrast-enhanced MR Imaging
48. Transient elastography in chronicliver diseases
49. Portal Venography
50. Minilaparoscopy and Conventional Laparoscopy
51. MEDICAL NUTRITION THERAPY IN LIVER DISEASE
52. Molecular Targets in Liver Disease
53. Specific Medications for Chronic Viral Hepatitis
54. Portal Vein Embolization (PVE) and Partial Transileocolic PVE with Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy-Beyond the Limitations of PVE
55. Endoscopic and Pharmacological Treatment of Esophageal Varices
56. Procedure for Gastric Variceal Bleeding - From BRTO to PARTO to CARTO, 3 Decades of Progress
57. Endoscopy and endoscopic ultrasound for the evaluation and treatment of gastric and ectopic varices
58. Portacaval Shunting for Portal Hypertension
59. Systemic Therapy of Advanced Liver Cancer
60. Embolization Therapy for Liver Cancer
61. Ablation of Hepatocellular Carcinoma
62. Laparoscopic Liver Resection
63. New locoregional approaches to treat liver cancer
64. Hepatic Encephalopathy
65.Management of ascites
66. Extracorporeal Non Cellular Liver Assisted Devices
67. Extracorporeal Cellular Liver Assisted Devices
68. Liver Transplantation for Acute and Chronic Liver Failure
69. Pre and Post Surgical Complications of Liver Transplantation
70. Anesthesia in Liver Transplantation
71. Surgery in Liver Disease
72. Robotic Liver Surgery
73. Cardiac surgery risks in liver dysfunction
74. Future Approaches in Liver Disorders: Regenerative Medicine.



ISBN 978-3-030-24434-7
Artikelnummer 9783030244347
Medientyp Buch
Auflage 1st ed. 2020
Copyrightjahr 2021
Verlag Springer, Berlin
Umfang X, 827 Seiten
Abbildungen X, 827 p. 247 illus., 203 illus. in color.
Sprache Englisch