Liver Radioembolization with 90Y Microspheres
E-Book
Liver Radioembolization with 90Y Microspheres
This book provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. Radioembolization combines embolization (intravascular deployment of particles microspheres loaded with yttrium-90) and brachytherapy (local administration of radiotherapy), thereby allowing delivery of high doses of beta-radiation specifically to the tumoral area in an attempt to overcome the problem of permanent radiation-induced damage to nontumoral liver parenchyma. Performance of the procedure demands close familiarity with the hepatic vascular anatomy in order to ensure avoidance of vessels going to other territories. Furthermore, a detailed knowledge of liver function, tumor volume, and liver vascular shunting is needed in order to calculate the appropriate therapeutic dose in each particular case. All of these topics are addressed in depth in this book, and initial promising clinical results are presented.
1;Contents;10 2;1. 90Y Microspheres: Concepts and Principles;12 3;2. Identification of Candidates and Selection Criteria;21 4;3. Radiological Evaluation of Patients with Liver Tumors;25 5;4. Vascular Anatomy and its Implication in Radioembolization;39 6;5. Radioembolization: Identyfying and Managing Anatomic Variants;53 7;6. Dosimetry and Dose Calculation;61 8;7. Improving Treatment Design by Image Fusion Techniques;70 9;8. Nuclear Medicine Procedures for Treatment Evaluation;83 10;9. Radiological Detection and Assessment of Tumor Response;100 11;10. Results in Hepatocellular Carcinoma;114 12;11. Results in Liver Metastatic Colorectal Cancer;123 13;12. 90Y Microspheres for Other Liver Metastases;131 14;13. Use of 90Y SIR-Spheres in the Treatment of Unresectable Hepatic Metastases from Neuroendocrine Tumors;141 15;14. Complications and Side Effects;144 16;15. Future Directions in Radioembolization;152 17;Subject Index;162 18;List Of Contributors;166
Bilbao, Jose I.
Reiser, Maximilian F.
| ISBN | 9783540354239 |
|---|---|
| Artikelnummer | 9783540354239 |
| Medientyp | E-Book - PDF |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2009 |
| Verlag | Springer-Verlag |
| Umfang | 164 Seiten |
| Sprache | Englisch |
| Kopierschutz | Adobe DRM |
