This is the second edition of a very well received book devoted specifically to the treatment of liver tumors by radioembolization with 90 Y microspheres. The success of the first edition was based on the provision of all the fundamental information required for successful use of this therapeutic modality in clinical practice. The new edition has been fully updated to cover the most recent advances and includes additional chapters on regulations and emerging trends. Detailed information is provided on the full range of relevant topics, including hepatic vascular anatomy (including variants), dosimetry, assessment of tumor response, and the results achieved using radioembolization alone and in combination with other treatments in patients with primary or metastatic disease. Complications and side-effects are also fully discussed. This book will prove immensely valuable for both beginners and practitioners.

Introduction

90Y Microspheres: Concepts and Principles
Regulations and requirements of hospitals performing radioembolization
Radiological evaluation of patients with liver tumors
Vascular anatomy and its implication in radioembolization
Radioembolization: Identifying and managing anatomic variants
Dosimetry and Dose Calculation
Nuclear Medicine Procedures for Treatment Evaluation
Histologic evaluation after Liver Radioembolization
Radiological Detection and Assessment of Tumor Response
Evaluation of the response by multimodality imaging
Results in hepatocellular carcinoma
Radioembolization combined with other therapeutic local and systemic treatments in hepatocellular carcinoma
Results in Liver Metastatic Colorectal Cancer
Radioembolization combined with other therapeutic local and systemic treatments in colorectal liver metastases
Use of Yttrium-90 Radioembolization in the Treatment of Unresectable Hepatic Metastases from Neuroendocrine Tumors
Ytrium 90 Radioembolization for other liver metastases
Complications and side effects
Radioembolization Induced Liver Disease
Future Directions in Radioembolization.