Lymphocytic Choriomeningitis Virus and Other Arenaviruses

Symposium held at the Heinrich-Pette-Institut für experimentelle Virologie und Immunologie, Universität Hamburg, October 16-18, 1972

Lymphocytic Choriomeningitis Virus and Other Arenaviruses

Symposium held at the Heinrich-Pette-Institut für experimentelle Virologie und Immunologie, Universität Hamburg, October 16-18, 1972

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Four decades ago, lymphocytic choriomeningitis virus was discovered, at about the same time and independently, in 3 different localities in the U.S.A. Armstrong and Lillie encountered the agent in a monkey when they passaged a recent isolate of the St. Louis encephalitis virus; Rivers and Scott isolated 5 strains from patients with meningitis; and Traub revealed the virus in a colony of albino mice. Already in these first isolations mice were incriminated, and later observa tions proved beyond doubt that M. musculus is the principal reservoir of the virus in nature. For some time LCM virus was regarded as the sole etiologic agent of Wallgren's "meningite aseptique aigue". Soon, however, it became clear that Wallgren's syndrome had a multitude of causes, among which the LCM virus was of little relevance, and in subsequent years it disappeared from the sight of most viro logists. Indeed, it might have fallen into oblivion had it not been for Erich Traub who, practically all by himself, continued to investigate the intricate relationship between this virus and its natural host, the common house mouse.

General Introduction
LCM Virus Research, Retrospect and Prospects
Lymphocytic Choriomeningitis Virus
The Virus: Purification, Chemical and Physical Properties, Complement-Fixing Antigen (s)
LCM Virus: Its Purification and its Chemical and Physical Properties
Antigenic Properties of the LCM Virus: Virion and Complement-Fixing Antigen
Electron Microscopy of LCM Virus-Infected L Cells
Interaction of LCM Virus with Cells, Including New Virus-Induced Cellular Antigens
Antigenic Alteration of Cells in Vitro Infected with LCM Virus
In Vitro Correlates of LCM Virus-Induced Immune Response
Histocompatibility and Lymphocytic Choriomeningitis Virus Infection
Persistent Infection in Vitro and in Vivo, Including Interference Phenomena
Cyclical Transient Infection, An Explanation of Persistent Virus Infection
Plaque Assays and Current Concepts of Regulation in Arenavirus Infections
Inapparent Infection of Syrian Hamsters with the Virus of Lymphocytic Choriomeningitis
Congenital LCM Virus Infection in "Germ-Free" Haas Strain Mice
LCM Virus-Induced Hemopoietic Disorder in Mice and its Role in the Induction of Tolerance
Murine LCM Virus Infection: Tolerance and Immunity
Inhibition of Mouse Tumors and Viruses by the M-P Strain of LCM Virus
Acute and Chronic LCM Disease in Man and Animals
Acute and Chronic LCM Disease
On the Pathogenesis of LCM Disease: Effects of Immunosuppression with Anti-Lymphocyte Serum
Thymus-Dependent (T) Cell Competence in Chronic LCM Virus Infection
Pathogenesis of LCM Disease in the Rat
In Vitro Measurement of the Time Course of Cellular Immunity to LCM Virus in Mice
LCM Disease of the Adult Rat: Morphological Alterations of the Brain
Epidemiologic Aspects of Lymphocytic Choriomeningitis in Man
OtherArenaviruses
Hemorrhagic Fever Group
Biology of Tacaribe-Complex Viruses
Biophysical and Biochemical Studies of Pichinde Virus
Ultrastructural Studies of Arenaviruses
Tamiami Virus-Induced Immunopathological Disease of the Central Nervous System
The Pathogenesis of Tamiami Virus Meningoencephalitis in Newborn Mice
Behavior of Machupo and Latino Viruses in Calomys callosus from Two Geographic Areas of Bolivia
Lassa Fever Virus
Lassa Fever Virus.
ISBN 978-3-540-06403-9
Artikelnummer 9783540064039
Medientyp Buch
Copyrightjahr 1973
Verlag Springer, Berlin
Umfang XIV, 342 Seiten
Abbildungen XIV, 342 p. 54 illus.
Sprache Deutsch, Englisch