This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein-protein interactions in the human adenovirus capsid, to mention but a few.

The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority.

Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Chapter 1. Structure, Dynamics and Function of the 26S Proteasome

Chapter 2. Factor VIII and Factor V Membrane Bound Complexes
Chapter 3. An Overview of DPS: Dual Acting Nanovehicles in Prokaryotes with DNA Binding and Ferroxidation Properties
Chapter 4. Structure and Function of the Separase-Securin Complex
Chapter 5. The DNA Replication Machine: Structure and Dynamic Function
Chapter 6. Recent Progress in Structural Studies on the GT-C Superfamily of Protein Glycosyltransferases
Chapter 7. How Structures of Complement Complexes Guide Therapeutic Design
Chapter 8. Architecture and Assembly of the Bacterial Flagellar Motor Complex
Chapter 9. Cellulosomes: Highly Efficient Cellulolytic Complexes
Chapter 10. Leucine Dehydrogenase: Structure and Thermostability
Chapter 11. Structure, Function and Physiology of 5-Hydroxytryptamine Receptors Subtype 3
Chapter 12. The SF3b Complex Is an Integral Component of the Spliceosome and Targeted byNatural Product-based Inhibitors
Chapter 13. Interaction Networks of Ribosomal Expansion Segments in Kinetoplastids
Chapter 14. Hepatitis B Core Protein Capsids
Chapter 15. Fibrinogen and Fibrin
Chapter 16. Structural Organization and Protein-protein Interactions in Human Adenovirus Capsid
Chapter 17. A Structural Perspective on Gene Repression by Polycomb Repressive Complex 2
Chapter 18. Assembly and Function of the Anthrax Toxin Protein Translocation Complex.