The position of "Cancer Teaching Coordinator" at The University of Chicago has been a consistently rewarding one because of the enthusiasm and support of the faculty and the students. This volume is the result of the second of two recent intensive teach ing sessions which have been planned and implemented by the group which forms the Cancer Coordinator's Advisory Committee. The first of these teaching sessions was held in early March of 1964 and was entitled "LEUKEMIA, A Current and Forward Look. " It attracted overflow attendance from the students and staff of this medical institution augmented by members of the other medical centers in Chicago. It was a stimulating and instructive colloquium, and the only regret we heard expressed afterward was that we had not arranged for publication of the many excellent presentations. One of the events commemorating the seventy-fifth anniversary of the founding of The University of Chicago was this symposium on malignant transformations. This time the Committee advised us to plan on speedy publication, and, logically, it chose Dr. Werner Kirsten, a member of our faculty and an active and effective investigator in this general field of endeavor, to serve as editor of the volume. Again, two of the same ingredients for effective instruction were blended: an excellent group of scientists presenting their latest work and a fine, attentive audience of students and staff.

The Characteristics of Malignant Transformation by Viruses

Malignant Transformation and Reversion of Virus Infected Cells
Discussion
Malignant Conversion by Avian Sarcoma Virus
Discussion
Epigenetic Factors in the Neoplastic Response to Polyoma Virus
Discussion: The Response of Metanephric Rudiments to Polyoma Virus In Vitro
Transformation by Mammary Tumor Agent in Tissue Culture
Discussion
Genetics and Immunology of Malignant Transformation by Viruses
Specific Antigens Produced by Oncogenic Viruses
Discussion
Complementation Between Defective Oncogenic Viruses
Discussion: Studies on Transformation by the Adenovirus-SV40 Hybrid Viruses
Cytogenetic Alterations During Malignant Transformation
Discussion: Relative Growth and Oncogenic Potential of Normal, Malignant, and Virus-transformed Euploid Cells of Dwarf Species of Hamster
Viruses and Human Neoplasm
Significance of Malignant Transformation in Relation to Human Neoplasms
Transformation of Human Cells by Oncogenic Virus SV40
Discussion
Immunologic Attack on Neoplasia
Round Table Discussion
Summary of the Symposium.