This book provides a comprehensive, state-of-the-art review of the concepts vital to a modern treatment of common and opportunistic infections in the immunocompromised host. Chapters are written by experts in the field, and include their views on gaps in the field and future directions of research. This book begins with an overview of the normally functioning immune system followed by a detailed discussion of the major primary immunodeficiencies. Specific chapters are dedicated to providing practical knowledge in the prevention and treatment of infections in specific immunocompromised patients, including those with cancer, transplant recipients, HIV infection, and autoimmune disorders. Emphasis is placed on diagnostic evaluation, antimicrobial selection that includes consideration of the threat of antimicrobial-resistant pathogens, and immunotherapy tailored to specific patients. Finally, dedicated chapters on stem cell transplantation for patients with primary immunodeficiencies,adoptive cellular immunotherapy, and gene therapy will provide readers with insight into these rapidly evolving and cutting edge therapies.Management of Infections in the Immunocompromised Host is a valuable resource for infectious diseases specialists, immunologists, oncologists, hematologists, general physicians, students, researchers, and all other working with immunocompromised patients.

1.Phagocytes

2.T-cells
3.B cell Immunity
4.Complement
5.Antimicrobial peptides
6.Role of Deficits in Pathogen Recognition Receptors in Infection Susceptibility
7.Defects of Innate Immunity
8.T Cell Defects
9.Inflammatory Bowel Disease in Primary Immunodeficiencies
10.Infections in Cancer.-  11.Infections in Hematopoietic Stem Cell Transplant Recipients
12.Infections in Solid Organ Transplant Recipients
13.Infections in HIV infected patients
14.Infections in Patients with Autoimmune Diseases
15.Antibacterials and antifungals: The Challenges of Antibiotic-Resistant Infections in the Immunocompromised Host
16.Antiviral treatment and prophylaxis in immunocompromised hosts
17.Role of Immunoglobulin Therapy to Prevent and Treat Infections
18.Vaccination of Immunocompromised Patients
19..Stem Cell Transplantation for Primary Immunodeficiency
20.Specific Adoptive T-cell Therapy for Viral and Fungal Infections
21.Gene Therapy for Primary Immunodeficiencies.