Skin cancer is the most common malignant neoplasm and its incidence is rising worldwide. The epidemic increase in such tumors calls for efficient management by the application of appropriate guidelines for therapy and prevention. Clinicians managing these patients need to keep up to date with the latest advances, allowing them to provide optimal treatment. This practical guide offers the reader a comprehensive overview of the options for the diagnosis, treatment, and prevention of cutaneous cancer. It covers all common skin cancers and also rarer lesions. Employing an 'evidence-based medicine' approach, this truly international work presents a well-illustrated text in a reader-friendly format with step-by-step guidelines and visual flowcharts. Dermatologists, oncologists, and all other interested physicians will find this book an extraordinarily valuable resource for the clinical management of cutaneous cancer in their daily practice.
1;Preface;5 2;Acknowledgements;6 3;Contents;7 4;Contributors;9 5;Chapter 1;12 5.1;Diagnosis of Skin Cancer;12 5.1.1;1.1 Clinical Evaluation and Risk Assessment;12 5.1.1.1;1.1.1 Actinic Keratosis and Squamous Cell Carcinoma;14 5.1.1.2;1.1.2 Basal Cell Carcinoma;16 5.1.1.3;1.1.3 Melanocytic Nevi;18 5.1.1.4;1.1.4 Malignant Melanoma;20 5.1.2;1.2 Noninvasive Imaging Techniques;21 5.1.2.1;1.2.1 Dermoscopy;21 5.1.2.2;1.2.2 Ultrasound;22 5.1.2.3;1.2.3 Optical Coherence Tomography;22 5.1.2.4;1.2.4 Refl ectance Confocal Microscopy;23 5.1.2.4.1;1.2.4.1 RCM Imaging of Actinic Keratosis (AK) and Squamous Cell Carcinoma (SCC);24 5.1.2.4.2;1.2.4.2 Imaging of Basal Cell Carcinoma (BCC);24 5.1.2.4.3;1.2.4.3 Melanocytic Nevi and Melanoma;24 5.1.3;1.3 Biopsy;25 5.1.3.1;1.3.1 Punch Biopsy;25 5.1.3.2;1.3.2 Shave Biopsy;25 5.1.3.3;1.3.3 Excisional Biopsy;25 5.1.3.4;1.3.4 Incisional Biopsy;25 5.1.4;References;25 6;Chapter 2;27 6.1;Histopathology of Skin Cancer;27 6.1.1;2.1 Basal Cell Carcinoma;27 6.1.2;2.2 Squamous Cell Carcinoma In Situ;30 6.1.2.1;2.2.1 Actinic Keratosis;30 6.1.2.1.1;2.2.1.1 Histology Appearance;31 6.1.2.1.1.1;Reference;32 6.1.2.2;2.2.2 Bowen's Disease;33 6.1.2.2.1;2.2.2.1 Erythroplasia of Queyrat;33 6.1.2.2.2;2.2.2.2 Bowenoid Papulosis;33 6.1.3;2.3 Invasive Squamous Cell Carcinoma;34 6.1.3.1;2.3.1 Acantholytic Squamous Cell Carcinoma;35 6.1.3.2;2.3.2 Spindle Cell Squamous Cell Carcinoma;35 6.1.3.3;2.3.3 Verrucous Squamous Cell Carcinoma;35 6.1.3.4;2.3.4 Adenosquamous Carcinoma;36 6.1.3.5;2.3.5 Keratoacanthoma (KA), Variants of SCC;36 6.1.4;2.5 Merkel cell carcinoma;40 6.1.4.1;References;40 6.1.5;2.6 Kaposi's Sarcoma;41 6.1.6;2.7 Dermatofi brosarcoma Protuberans;42 6.1.7;2.8 Atypical Fibroxanthoma;43 6.1.8;2.9 Malignant Fibrous Histiocytoma;44 6.1.8.1;References;44 7;Chapter 3;46 7.1;Basal Cell Carcinoma;46 7.1.1;3.1 Introduction/Epidemiology;46 7.1.2;3.2 Pathogenesis;47 7.1.3;3.3 Clinical/Histological Variants;48 7.1.4;3.4 Diagnosis/Work Up/Risk Factor Assessment;49 7.1.5;3.5 Treatment;49 7.1.5.1;3.5.1 Methods of Treatment;50 7.1.5.1.1;3.5.1.1 Destructive;50 7.1.5.1.1.1;Curettage and Electrodesiccation (CE);50 7.1.5.1.1.2;Cryosurgery;50 7.1.5.1.1.3;Radiation Therapy (RT);51 7.1.5.1.1.4;Photodynamic Therapy (PDT);51 7.1.5.1.1.5;Laser Therapy;52 7.1.5.1.2;3.5.1.2 Surgical;52 7.1.5.1.2.1;Excision with Postoperative Margin Assessment (POMA);52 7.1.5.1.2.2;Mohs Micrographic Surgery (MMS);52 7.1.5.1.3;3.5.1.3 Pharmacological Treatments;53 7.1.5.1.3.1;Interferon (IFN);53 7.1.5.1.3.2;Topical Chemotherapy;53 7.1.5.1.3.3;Retinoids;53 7.1.5.1.3.4;Immune Response Modifi er;53 7.1.5.1.3.5;Systemic Chemotherapy;54 7.1.5.1.3.6;Follow-Up;54 7.1.6;References;54 8;Chapter 4;59 8.1;Squamous Cell Carcinoma In Situ;59 8.1.1;4.1 Actinic Keratoses;59 8.1.1.1;4.1.1 Epidemiology and Ethiopathogenesis;59 8.1.1.2;4.1.2 Clinic;60 8.1.1.3;4.1.3 Histopathology;61 8.1.1.4;4.1.4 Treatment;61 8.1.1.4.1;4.1.4.1 Surgical Excision, Curettage;62 8.1.1.4.2;4.1.4.2 Cryotherapy;62 8.1.1.4.3;4.1.4.3 Chemical Peeling;62 8.1.1.4.4;4.1.4.4 Laser;62 8.1.1.4.5;4.1.4.5 Radiation;62 8.1.1.4.6;4.1.4.6 Photodynamic Therapy;62 8.1.1.4.7;4.1.4.7 Imiquimod;63 8.1.1.4.8;4.1.4.8 Topical 5-Fluorouracil;63 8.1.1.4.9;4.1.4.9 Retinoids;63 8.1.1.4.10;4.1.4.10 Diclofenac in Hyaluronic Acid Gel;63 8.1.1.5;4.1.5 Prevention;64 8.1.2;4.2 Bowen's Disease;64 8.1.2.1;4.2.1 Epidemiology and Etiopathogenesis;64 8.1.2.2;4.2.2 Clinic and Diagnosis;64 8.1.2.3;4.2.3 Treatment;65 8.1.2.3.1;4.2.3.1 Excision;65 8.1.2.3.2;4.2.3.2 Curettage and Electrodissecation;65 8.1.2.3.3;4.2.3.3 Photodynamic Therapy;65 8.1.2.3.4;4.2.3.4 Cryotherapy;65 8.1.2.3.5;4.2.3.5 5-Fluorouracil;65 8.1.2.3.6;4.2.3.6 Imiquimod;65 8.1.3;References;65 9;Chapter 5;68 9.1;Invasive Squamous Cell Carcinoma of the Skin;68 9.1.1;5.1 Epidemiology and Etiopathogenesis;68 9.1.1.1;5.1.1 Epidemiology;68 9.1.1.2;5.1.2 Etiology;69 9.1.1.3;5.1.3 Pathogenesis;70 9.1.2;5.2 Clinical Presentation and Morphologic Variants of SCC;71 9.1.2.1;5.2.1 Typical
Stockfleth, Eggert
Rosen, Ted
Schumaak, Steven
| ISBN | 9783540793472 |
|---|---|
| Artikelnummer | 9783540793472 |
| Medientyp | E-Book - PDF |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2010 |
| Verlag | Springer-Verlag |
| Umfang | 226 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
