Marburg Virus Disease

Marburg Virus Disease

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in Vorbereitung

In the late summer of 1967, several patients suffering from a severe disease were admitted to the Department of Medicine of the Marburg University. It soon became obvious that the illness was a hitherto unknown infectious disease. The number of afflicted patients increased to 23. Several cases were observed in Frankfurt/Main at the same time and, some weeks later also in Belgrade, Yugo slavia. Common to all the patients was previous contact with the blood or tissues of Cercopithecus aethiops, the vervet monkey. Altogether 31 people became ill and 7 died. It was soon apparent that the infectious agent was neither bacterial nor rickettsial in origin but that a viral etiology was probable. Most of the known viral diseases were excluded and the infectious agent was shown to be a hitherto unknown virus with many peculiar characteristics: it infects guinea pigs but not adult mice and is larger than known viruses and of different shape. This agent was called the "Marburg virus" since most of the cases had occurred in Marburg and the greater part of the laboratory work leading to the detection of the virus was performed in Marburg.

Marburg Virus Disease. Clinical Syndrome
Clinical Course and Prognosis of Marburg Virus ("Green-Monkey") Disease
Clinical Picture of Two Patients Infected by the Marburg Vervet Virus
Two Cases of Cercopithecus-Monkeys-Associated Haemorrhagic Fever
Haematological Findings in Marburg Virus Disease: Evidence for Involvement of the Immunological System
Clinical Manifestations and Mechanism of the Haemorrhagic Diathesis in Marburg Virus Disease
Pathologic Anatomy of the Marburg Virus Disease
The Neuropathology of the Marburg Disease in Man
Marburg Virus Hepatitis
Morphology, Development, and Classification of the Marburg Virus
Morphology and Morphogenesis of the Marburg Agent
Absence of Serological Relationship Between the Marburg Virus and Some Arboviruses
Biological Properties of the Marburg Virus
Some Characteristics of the Marburg Virus
Cultivation of the Marburg Virus (Rhabdovirus simiae) in Cell Cultures
Passage of Marburg Virus in Guinea Pigs
Histologic Findings in Livers and Spleens of Guinea Pigs after Infection by the Marburg Virus
Neuropathological Findings in Experimentally Infected Guinea Pigs
"Marburg Disease". The Pathology of Experimentally Infected Hamsters
Experimental Infection of Monkeys with the Marburg Virus
The Morphological Picture in Livers, Spleens, and Lymph Nodes of Monkeys and Guinea Pigs after Infection with the "Vervet Agent"
Laboratory Diagnosis and Pathogenesis
Epidemiology of "Marburg Virus" Disease
Epidemiological Studies in Uganda Relating to the "Marburg" Agent
A Serological Survey of Primate Sera for Antibody to the Marburg Virus
Studies on the Marburg Virus
Examination of South African Primates for the Presence of Marburg Virus
Epizootic, Clinical, andPathological Aspects of Simian Hemorrhagic Fever
Simian Hemorrhagic Fever Virus
Measures Taken by the Public Health Officials During the "Marburg Virus Disease"
The Vervet Monkey Disease, Protection Against Occupational Hazards
Legislative Measures Concerning the Importation of Monkeys
W.H.O. Draft Recommendations for the Supply, Safe-Handling, and Use of Non-Human Primates for Biomedical Purposes
Marburg Virus: Consequences for the Manufacture and Control of Virus Vaccines.
ISBN 9783662015957
Artikelnummer 9783662015957
Medientyp Buch
Auflage 1971
Copyrightjahr 2014
Verlag Springer, Berlin
Umfang 231 Seiten
Abbildungen VII, 231 p. 98 illus.
Sprache Englisch