The idea for publishing these books on the mechanism of action and on the biosynthesis of antibiotics was born of frustration in our attempts to keep abreast of the literature. Gone were the years when we were able to keep a biblio graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for ward so rapidly and were encompassing so wide a range of specialized areas in microbiology and chemistry that it was almost impossible to keep abreast of developments. In our naivete and enthusiasm, however, we were unaware that we were toying with an idea that might enmesh us, that we were creating an entity with a life of its own, that we were letting loose a Golom who instead of being our servant would be our master. That we set up ideals for these books is obvious; they would be current guides to developments and information in the areas of mechanism of action and bio synthesis of antibiotics. For almost every subject, we wished to enlist the aid of an investigator who himself had played a part in determining the nature of the phenomena that were being discussed. One concept for the books was that they include only antibiotics for which a definitive, well-documented mechanism of action or biosynthetic pathway was known.

Penicillins and Cephalosporins, I. In Vitro

Penicillins and Cephalosporins, II. In the Host
Addendum - Penicillin-Cephalosporin: E. H. Flynn and C. W. Godzeski
D-Cycloserine and O-Carbamyl-D-serine
Ristocetin
Bacitracin
Vancomycin
Pyocyanine
Polyene Antibiotics
Addendum - Polyenes S. C. Kinsky
Polymyxins and Circulin
Addendum - Polymyxins and Circulin O. K. Sebek
Albomycin
Sarkomycin
Addendum - Sarkomycin: S. C. Sung
Pluramycin
Edeine and Pactamycin
Phleomycin, Xanthomycin, Streptonigrin, Nogalamycin, and Aurantin
Griseofulvin
Daunomycin and Related Antibiotics
The Mitomycins and Porfiromycins
Chromomycin, Olivomycin and Mithramycin
Puromycin
Gougerotin
Cycloheximide and Other Glutarimide Antibiotics
Chloramphenicol
Addendum - Chloramphenicol: F. E. Hahn
Addendum - Chloramphenicol: P. D. Shaw
Tetracyclines
Addendum - Tetracyclines: A. I. Laskin
Tenuazonic Acid
Macrolide Antibiotics - Spiramycin, Carbomycin, Angolamycin, Methymycin and Lancamycin
Addendum - Streptogramin and Macrolide Antibiotics: D. Vazquez
Erythromycin and Oleandomycin
Addendum - Erythromycin: F. E. Hahn
The Streptogramin Family of Antibiotics
Addendum - Streptogramin and Macrolide Antibiotics: D. Vazquez
Fucidin
Sparsomycin
Addendum -Sparsomycin: D. Gottlieb
Rifamycins
Nucleocidin
Blasticidin S
Lincomycin
Chalcomycin
Hadacidin
Psicofuranine
Angustmycin A
Cordycepin
Addendum - Cordycepin: A. J. Guarino
Azaserine and 6-Diazo-5-Oxo-L-Norleucine (DON)
Tubercidin and Related Pyrrolopyrimidine Antibiotics
Sideromycins
Addendum -Sideromycins: J. NüEsch and F. Knüsel
Antimycin A
Addendum - Antimycin A: J. S. Rieske
Oligomycin Complex, Rutamycin and Aurovertin
UsnicAcid
Nigericin
Flavensomycin
Patulin
Valinomycin
Addendum - Valinomycin: P. D. Shaw
Tyrocidines and Gramicidin S (J1, J2)
Gramicidins
Nonactin and Related Antibiotics
Addendum - Nonactin: P. D. Shaw
Novobiocin
Addendum - Novobiocin: D. Gottlieb
Actithiazic Acid
Minomycin
Protoanemonin
Trichothecin
Viomycin
Addendum -Viomycin: P. D. Shaw
Actinomycetin
Bacteriocins
Megacins
Colicin
Addendum - Colicin: D. Gottlieb
Enzymatic Reactions in Bacterial Cell Wall Synthesis Sensitive to Penicillins, Cephalosporins and Other Antibacterial Agents
Actinomycin
The Effect of Streptomycin and Other Aminoglycoside Antibiotics on Protein Synthesis
Addenda
Antibiotic U-20, 66l: F. Reusser
Antibiotic 6270 (Echinomycin-like): D. Gottlieb
Amicetin: D. Gottlieb
Bruneomycin: D. Gottlieb
Phytoactin: D. Gottlieb
List of Antibiotics According to Their Sites of Action.