Memories: Molecules and Circuits
Molecules and Circuits
Memories: Molecules and Circuits
The questions of how, where and when memory traces are formed in the brain remain central issues in Cognitive Neuroscience. How do neuronal systems encode, consolidate and retrieve memory? How are memories embedded into complex neuronal networks? How do molecular mechanisms modulate the neuronal plasticity and functioning of these networks during memory processing? What are the fundamental units of computation in the brain? Thanks to the development of novel approaches, including transgenic techniques, functional brain imaging, multiple cell recording, functional genomics and proteomics, the last decade has been witness to dramatic advances in the neurobiology, neuroanatomy, neurophysiology and neuropathology of learning and memory processes.
This volume surveys the recent advances and provides an integrative view of molecular, cellular, and systems level mechanisms underlying cognitive processes in both animals and humans. Current state of the art and future avenues are discussed by distinguished scientists who provide not only an overview of the underlying neurobiology of cognitive processes from a basic science standpoint, but who also focus on clinical and therapeutic aspects surrounding impairments associated with disorders that affect cognition.
The questions of how, where and when memory traces are formed in the brain remain central issues in Cognitive Neuroscience. How do neuronal systems encode, consolidate and retrieve memory? How are memories embedded into complex neuronal networks? How do molecular mechanisms modulate the neuronal plasticity and functioning of these networks during memory processing? What are the fundamental units of computation in the brain? Thanks to the development of novel approaches, including transgenic techniques, functional brain imaging, multiple cell recording, functional genomics and proteomics, the last decade has been witness to dramatic advances in the neurobiology, neuroanatomy, neurophysiology and neuropathology of learning and memory processes.
This volume surveys the recent advances and provides an integrative view of molecular, cellular, and systems level mechanisms underlying cognitive processes in both animals and humans. Current state of the art and future avenues are discussed by distinguished scientists who provide not only an overview of the underlying neurobiology of cognitive processes from a basic science standpoint, but who also focus on clinical and therapeutic aspects surrounding impairments associated with disorders that affect cognition.
1;Preface;5 2;Table of Contents;8 3;Contributors;9 4;The Neuroanatomy and Neuropsychology of Declarative and Nondeclarative Memory;12 5;Dynamics of Hippocampal-Cortical Interactions During Memory Consolidation: Insights from Functional Brain Imaging;30 6;From Molecule to Memory System: Genetic Analyses in Drosophila;51 7;Towards a Molecular and Cellular Understanding of Remote Memory;68 8;Post-Activation State: A Critical Rite of Passage of Memories;77 9;Reactivation-Dependent Amnesia: Disrupting Memory Reconsolidation as a Novel Approach for the Treatment ofMaladaptive Memory Disorders;91 10;TheOrganizing Principles of Real-Time Memory Encoding: Neural Clique Assemblies and Universal Neural Codes;107 11;Making and Retaining NewMemories: The Role of the Hippocampus in Associative Learning and Memory;121 12;Entorhinal Grid Cells and the Representation of Space;133 13;The Prefrontal Cortex: Categories, Concepts, and Cognitive Control;144 14;Molecules that Disrupt Memory Circuits in Alzheimer's Disease: The Attack on Synapses by Aß Oligomers ( ADDLs);162 15;Subject Index;187
Bontempi, Bruno
Silva, Alcino J.
Christen, Yves
ISBN | 9783540457022 |
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Artikelnummer | 9783540457022 |
Medientyp | E-Book - PDF |
Auflage | 2. Aufl. |
Copyrightjahr | 2007 |
Verlag | Springer-Verlag |
Umfang | 182 Seiten |
Sprache | Englisch |
Kopierschutz | Digitales Wasserzeichen |