1 Basics of Lymphology

1.1 Embryology and Anatomy
1.2 Physiology and Pathophysiology
References
2 Lymphogenic Metastatic Spread
2.1 Squamous Cell Carcinomas
2.2 Malignant Melanoma
2.3 Merkel Cell Carcinoma
2.4 Carcinomas of the Salivary Glands
2.5 Carcinomas of the Thyroid Gland
References
3 The Pathology of Lymphogenic Metastatic Spread
3.1 Examination Methods
3.2 Squamous Cell Carcinomas of the Head and Neck
3.3 Metastases of Salivary Gland Tumors and Thyroid Gland Carcinomas
3.4 Uncommon Cervical Lymph Node Metastases
3.5 Non-Neoplastic Reactive Lymph Node Alterations
References
4 Diagnostic Techniques
4.1 Introduction
4.2 Inspection and Palpation
4.3 B-Mode Sonography
4.4 Computed Tomography and Magnetic Resonance Imaging
4.5 Lymphoscintigraphy
4.6 Positron Emission Tomography
4.7 Lymphography
4.8 Lymph Node Biopsy
4.9 Conclusion
References
5 Principles of Surgery
5.1 History and Classification of the Surgical Treatment of Cervicofacial Lymph Node Metastases
5.2 Decision Points in Neck Dissection
6 Radiation Therapy: Principles and Treatment
6.1 Elective Neck Irradiation
6.2 Postoperative Radiation of the Node Positive Neck
6.3 Intensity-Modulated Radiation Therapy
6.4 Future Potential Applications
References
7 Surgical Treatment Concepts
7.1 The Role of Neck Dissection in the Treatment of Squamous Cell Carcinomas of the Upper Aerodigestive Tract
7.2 Neck Dissection for Lymphoepithelial Carcinomas
Neck Dissection for Skin Malignancies
7.4 Neck Dissection for Carcinomas of the Salivary Glands
7.5 Neck Dissection for Carcinomas of the Thyroid Gland
7.6 Sentinel Node Biopsy
7.7 Conclusion
References
8 Complications
8.1 Surgical Complications
8.2 Complications from Radiation Therapy
References
9 Cancer of Unknown Primary Sites
9.1 General Considerations
9.2 Topography of Lymph Node Metastases in Cancer of Unknown Primary
9.3 Diagnostics
9.4 Prognosis in Patients with Cancer of Unknown Primary Site
9.5 Treatment Concepts of Lymph Node Metastases in Sqamous Cell Carcinoma of Unknown Primary Site
9.6 Treatment Concepts of Lymph Node Metastases in Adenocarcinoma
9.7 Treatment Concepts of Lymph Node Metastases in Occult Malignant Melanoma
9.8 Value of Post-Therapeutic Appearance of the Primary Cancer
9.9 Branchiogenic Carcinoma
References
10 Distant Metastases
10.1 Nasopharynx
10.2 Lips and Anterior Oral Cavity
10.3 Oropharynx
10.4 Larynx and Hypopharynx
10.5 Cervical Esophagus
10.6 Salivary Glands
10.7 Thyroid Gland
References
11 Post-Therapeutic Follow-Up Principles
11.1 General Considerations
11.2 Follow-Up Interval
11.3 Type, Extent and Costs of Follow-up Examinations
References.