Discover a comprehensive overview of efficient synthetic routes to an important compound class in organic and pharmaceutical chemistry

Methodologies in Amine Synthesis: Challenges and Applications delivers powerful and state-of-the-art methods for the efficient preparation of amines. The text summarizes recent advances in the electrophilic amination reaction, hydroamination, C-H amination and newly developed photocatalytic approaches. The distinguished editor has included resources that discuss organocatalytic and enzymatic routes to the generation of amines under mild and environmentally friendly conditions.

The book also highlights the relevance of the amino function in bioactive molecules, drugs, and smart materials, as well as the palladium-catalyzed aromatic amination reaction. It presents efficient and practical synthetic methods, highlights the opportunities and challenges associated with each, and discusses their possible applications in pharmaceutical chemistry and materials science.

Edited by the expert who wrote Modern Amination Methods and Amino Group Chemistry, the book includes a breadth and depth of material essential to the practice of academic and industrial chemists working in organic synthesis and catalysis. Readers will also benefit from the inclusion of:

• A thorough introduction to new openings and perspectives in the electrophilic amination
• Discussions of asymmetric catalysed hydroaminomethylation and amino organocatalysis
• A treatment of the synthetic application of transaminase or MAO biocatalysis to the synthesis of amines
• An exploration of recent developments in C-H amination, as well as photocatalytic approaches to the synthesis of amines
• An examination of primary amines from renewable bio-based resources

Perfect for organic, natural product, catalytic, medicinal, and polymer chemists, Methodologies in Amine Synthesis: Challenges and Applications will also earn a place in the libraries of materials scientists and chemists working with organometallics who desire a one-stop reference edited by a well-known expert in the field.

Alfredo Ricci - after his retirement as Professor - is currently visiting scientist at the Department of Industrial Chemistry 'Toso Montanari' at Bologna University, Italy. He has authored more than 300 scientific publications and received several awards, including the 'French-Italian Prize for Organic Synthesis', the Merck-ADP Grants for Training of Younger Scientists, and the nomination as Fellow of the Japan Society for Promotion of Science (JSPS).

Luca Bernardi is Associate Professor at the Department of Industrial Chemistry 'Toso Montanari' at Bologna University, Italy. He is co-author of about 80 articles, two patents and four book chapters. He received the 'Thieme Journal Prize' in 2009 and the Ciamician Medal of the Organic Chemistry Division in 2010. His research is mainly directed at the development of new catalytic enantioselective reactions.