Microreaction technology is the logically consistent application of microsystem techniques in chemical reaction and process engineering. Miniaturization in this field is the strategy of success and requires the development of small, inexpensive, independent and versatile chemical reaction units. Microreaction technology is at present regarded as one of the fastest evolving and most promising disciplines in chemical engineering, combinatorial synthesis and analysis, pharmaceutical drug development and molecular biotechnology. A broad range of microstructurable materials is a prerequisite for microreaction technology and the development of microreactors goes hand in hand with the availability of a number of modem, versatile microfabrication technologies. Today, it is possible to manufacture tbree dimensional microstructures, almost without any restrictions with regard to design and choice of suitable materials, for various chemical applications -just in time to support the development of functional units for microreactors, e. g. micromixers, micro heat exchangers, micro extractors, units for phase transfer, reaction cham bers, intelligent fluidic control elements and microanalysis systems. The advantages of microreactors, e. g. the use of novel process routes, the re duction of reaction byproducts, the improvement of 'time to market', the high flexibility for all applications requiring modular solutions, have had a strong im pact on concepts of sustainable development. Many of the leading companies and research institutes in the world have recognized the tremendous possibilities of microreactor concepts and of their economic potential, and have thus initiated worldwide research and development activities.

1 Reaction Engineering Aspects of Microreaction Systems

Reaction Engineering for Microreactor Systems
Observations on Hypothetical Miniaturised, Disposable Chemical Plant
Monolithic Microreactors Possessing Regular Mesopore Systems for the Successful Performance of Heterogeneously Catalysed Reactions
Scouting Study about the Use of Microreactors for Gas Supply in a PEM Fuel Cell System for Traction
Solute Transfer by Liquid/Liquid Exchange without Mixing in Micro-Contactor Devices
Reactions in Microreactors in Electric Fields
High-Temperature Micro Catalysis: a New Design for Comperative Reaction Studies in Technical and Model Systems
Micro-Structure Electrodes as Electronic Interface between Solid and Gas Phase: Electrically Steerable Catalysts for Chemical Reactions in the Gas Phase
2 Design and Production of Microreactor Systems
Fabrication of Components and Systems for Chemical and Biological Microreactors
Technologies and Microstructures for (Bio)chemical Microsystems
Functionalized Biomolecular Membranes for Microreactors
Nano Titer Plates: Micro Compartment Arrays for Biotechnological Applications
An Automated Method to Create a One Dimensional Array of Chemically Synthesized Oligonucleotides
Development of a Microreactor for Chemical Production
Laser Processes for Flexible Manufacturing of Fluidic Micro Reactors
The Use of Microcapillaries and Catalytic Contact Printing for the Preparation of Microstructured Magnetic Surfaces and for the Ordered Deposition of Proteins on Surfaces
Fabrication and Interconnection of Ceramic Microreaction Systems for High Temperature Applications
Fabrication of Microreactor Components by Electro Discharge Machining
Silicon Microreactors made by Reactive Ion Etching
Porous Silicon as the Carrier Martix in a Micro Enzyme Reactor to Achieve a Highly Efficient and Long-Term Stable Glucose Sensor
3 Microreactors in Combinatorial Chemistry
MCR X. Important Aspects for Automating Preparative Chemistry
MCR XII. Efficient Development of New Drugs by Online-Optimization of Molecular Libraries
MCR XI. Microreactors as Processors for Chemical Computers
4 Application of Microreactors in Drug Development and Biotechnology
Microfabricated Devices for Performing Chemical and Biochemical Analysis
A New Design of a Wafer Based Micro Reaction System
A Silicon Microreactor for Immunological Applications
A Microflow Reactor for Two Dimensional Investigations of In Vitro Amplification Systems
Flourescence Correlation Spectroscopy (FCS), the Detection Method for Sub-Microliter Miniaturized Biological Assays
The Physiocontrol-Microsystem (PCM): Analysis of Cellular Behaviour for Biomedical Research
Development of a Pharmacological Test System in a Miniaturized Hollow Fiber Bioreactor
A Microreactor with On-line Mass Spectrometry for the Investigation of Biological Kinetics
Microarray Based Ligand Binding System
5 Application of Microreactors in Chemical Analysis and Diagnosis
Advantages Afforded by Miniaturization and Integration of DNA Analysis Instrumentation
Nanoscaled Impedimetric Sensors for Multiparameter Testing of Biochemical Samples
Temperature Controlled Chip Reactor for Rapid PCR
Incremental Parallel Microtitrtation: A Novel Approach Towards Test Strip Devices of Extreme Accuracy
Concept of Miniaturized and fast GC and HPLC Analytical Systems Integrated in Microreactors
Possibilities for Thermophysical Reaction Monitoring in Microreactors
Heating and Calorimetry in Single Droplets and Micro Fluid Reactors
Microreactions on the Surface of an Oligonucleotide Bearing Chip
Coulometric Nanotitrators with Potentiometrie Endpoint Detection
Miniaturization as a Demand of High-Throughput-Synthesis and -Analysis of Biomolecules.