Microstructural Parcellation of the Human Cerebral Cortex

From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging

Microstructural Parcellation of the Human Cerebral Cortex

From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging

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Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques - and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains.

This book starts with Brodmann's post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of "in vivo Brodmann mapping" using high-field MRI, which was introduced in the early 21st century.



Guy N. Elston, Laurence J. Garey: The cytoarchitectonic map of Korbinian Brodmann: Arealisation and circuit specialization

Lazaros C. Triarhou: The cytoarchitectonic map of Constantin von Economo and Georg N. Koskinas
Rudolf Nieuwenhuys: The myelo architectonic studies on the human cerebral cortex of the Vogt - Vogt school, and their significance for the interpretation of functional neuroimaging data
Bruce Fischl: Estimating the location of Brodmann Areas from cortical folding patterns using histology and ex vivo MRI
Simon B. Eickhoff, Danilo Bzdok: Database-driven identification of functional modules in the cerebral cortex
Robert Turner: Where matters: New approaches to brain analysis
Robert Turner: MRI methods for in-vivo cortical parcellation
Nicholas A. Bock, Afonso C. Silva: Visualizing myelo architecture in vivo with magnetic resonance imaging in common marmosets (Callithrix jacchus)
Stefan Geyer: High-field magnetic resonance mapping of the border between primary motor (area 4) and somatosensory (area 3a) cortex in ex-vivo and in-vivo human brains.


ISBN 978-3-642-37823-2
Artikelnummer 9783642378232
Medientyp Buch
Copyrightjahr 2013
Verlag Springer, Berlin
Umfang VIII, 257 Seiten
Abbildungen VIII, 257 p. 187 illus., 39 illus. in color.
Sprache Englisch