mene Stil in jeglicher Kunst, daft er die spezijischen Schranken derselben zu entfernen weip, ohne doch ihre spezijischen Vorzuge mit aufzuhe ben, und durch eine weise Benut zung ihrer Eigentumlichkeit ihr einen mehr allgemeinen Charakter erteilt. Friedrich Schiller - Ober die as the tische Erziehung des Menschen. In den Horen, 22. Brief (1795) We are glad that you have all come to this small village and I hope that you will feel at home here for the next few days. The special atmosphere of the surround ings will probably have a good influence on our discussions, and you will perhaps remember this when you are back home again. It takes hard work to save this little piece of nature for man in our highly industrialized world, and we should all be grateful to the Verein Naturschutzpark e. V. (founded in 1909), Alfred Toepfer and his associates for their efforts. We intend to discuss modern trends in human leukemia in this workshop, but we should also take the opportunity to reflect on the trends of the past, which might still be modern.

Cell Biology of Leukemia

Notions about the hemopoietic stem cell
Productivity in normal and leukemic granulopoiesis
Cytology and cytochemistry of colony cells in soft agar gel culture from normal and leukemic bone marrow
Cellular subclasses in human leukemic hemopoiesis
Characterisation and pathological growth of human bone marrow cells by means of a new stem cell assay
The phenotypic abnormality in leukemia: a defective cell-factor interaction?
In vitro colöny growth of acute myelogenous leukemia
Clinical utility of bone marrow culture
Proliferative behavior of hemopoietic cells in preleukemia and overt leukemia observed in one patient
Leukemic anaplasias reflecting physiologic cytogenesis of myeloid system
Membrane remodeling during phagocytosis in chronic myelogenous leukemia cells
Erythroid cell differentiation
Molecular mechanisms in erythroid differentiation
Analysis by computer controlled cell sorter of Friend virus-transformed cells in different stages of differentiation
Hormone independent in vitro erythroid colony formation by mouse bone marrow cells
In vitro and preliminary in vivo studies of compounds which induce the differentiation of Friend leukemia cells
Target cells for leukemic transformation by chicken C-type viruses
Fusion experiments with human tumour cells
Effect of cytochalasin B on malignant cells
Growth regulation and suppression of metastasis in the congenitally athymic nude mouse
Immunology of Leukemia
Cell-mediated immunity to leukemia associated antigens in experimental models and in man
Surface features of cells in human lymphoproliferative disorders. An immunoelectron microscopy study
Immunological characterization of blast cells in patients with acute lymphoblastic leukemias. Evaluation ofits clinical significance
Immunological membrane markers of Hodgkin's cells
Human leukemia-lymphoma associated antigen detected by heteroantisera
Analysis of human leukaemic cells using cell surface binding probes and the fluorescence activated cell sorter
Use of immunological reagents prepared in animals to characterise the surface of leukaemic cells
Therapy of Leukemia
Trends in the treatment of childhood leukemia
The therapy of acute leukemia in the adult. A progress report
Aids in the management of leukemia (cell removal by continuos flow leukapheresis and impulse cytophotometry)
The place of immunological methods of treatment in the management of acute leukaemia
Perspectives and prospectives in the management of acute leukemia
Oncogenic Viruses in Leukemia
Restricted addition of proviral DNA in target tissues of chickens infected with avian myeloblastosis virus
Sequences and functions of Rous sarcoma virus RNA
Infection of developing mouse embryos with murine leukemia virus: tissue specificity and genetic transmission of the virus
Type C virogenes: modes of transmission and evolutionary aspects
Bovine leukemia virus: an exogenous RNA oncogenic virus?
Molecular evidence for the association of RNA tumor viruses with human mesenchymal malignancies
RNA tumor viruses and leukemia: evaluation of present results supporting their presence in human leukemias
Murine and simian C-type viruses: sequences detected in the RNA of human leukemic cells by the c-DNA probes
Prevention of herpes-associated malignancies in primates: problems and prospects
New properties of mammalian cells transformed by herpes simplex and cytomegalo-viruses
Failure to immortalize human 'null' cells by Epstein Barr virus (EBV) 'in vitro'
The roleof viruses in human leukemia: a summary
RNA Synthesis and Translation in Leukemic Cells
IS-element in bacteria
Circadian variation of «-amanitine sensitive RNA-synthesis in normal human lymphocytes
Terminal deoxynucleotidyl transferase as a biological marker for human leukemia
Terminal deoxynucleotidyl transferase in normal and neoplastic hematopoietic cells
A new, not virus related reverse transcriptase in the chicken system
Translation level control in normal and leukemic cells
Control of peptide chain initiation in uninfected and virus infected cells by membrane mediated events
List of Participants.