Molecular Analysis of B Lymphocyte Development and Activation
Molecular Analysis of B Lymphocyte Development and Activation
The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
Gene Regulatory Networks Orchestrating B Cell Fate Specification, Commitment, and Differentiation
Helix-Loop-Helix Proteins in Lymphocyte Lineage DeterminationIkaros-Family Proteins: In Search of Molecular Functions During Lymphocyte Development
Biochemistry of V(D)J Recombination
The pre-B cell Receptor in B Cell Development: Recent Advances, Persistent Questions and Conserved Mechanisms
Transcriptional Control of B Cell Activation
Expression of MHC II Genes
Class Switch Recombination: An Emerging Mechanism
Blimp-1; Immunoglobulin Secretion and the Switch to Plasma Cells
Wnt Signaling in Lymphopoiesis.
Singh, Harinder
Grosschedl, Rudolf
| ISBN | 978-3-540-23090-8 |
|---|---|
| Artikelnummer | 9783540230908 |
| Medientyp | Buch |
| Copyrightjahr | 2005 |
| Verlag | Springer, Berlin |
| Umfang | XI, 260 Seiten |
| Abbildungen | XI, 260 p. |
| Sprache | Englisch |
