Molecular Drug Properties

Measurement and Prediction

Molecular Drug Properties

Measurement and Prediction

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This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation.

Raimund Mannhold is Professor for Molecular Drug Research at the University of Dusseldorf, Germany. His scientific interests lie with QSAR studies and related methods to determine and predict drug properties. He is a founding editor of the book series 'Methods and Principles in Medicinal Chemistry' and serves on the editorial boards of several journals in the field of medicinal chemistry and drug design.
ISBN 9783527621293
Artikelnummer 9783527621293
Medientyp E-Book - PDF
Copyrightjahr 2008
Verlag Wiley-VCH
Umfang 502 Seiten
Sprache Englisch
Kopierschutz Adobe DRM