This book discusses the most significant recent advances in oncological molecular imaging, covering the full spectrum from basic and preclinical research to clinical practice. The content is divided into five sections, the first of which is devoted to standardized and emerging technologies and probe designs for different modalities, such as PET, SPECT, optical and optoacoustic imaging, ultrasound, CT, and MRI. The second section focuses on multiscale preclinical applications ranging from advanced microscopy and mass spectroscopy to whole-body imaging. In the third section, various clinical applications are presented, including image-guided surgery and the radiomic analysis of multiple imaging features. The final two sections are dedicated to the emerging, crucial role that molecular imaging can play in the planning and monitoring of external and internal radiotherapy, and to future challenges and prospects in multimodality imaging. Given its scope, the handbook will benefit allreaders who are interested in the revolution in diagnostic and therapeutic oncology that is now being brought about by molecular imaging.

Computed tomography and magnetic resonance imaging.- Single photon emission computed tomography - tracer.- Non-peptidyl ¹⁸F-labelled PET tracers as radioindicators for the noninvasive detection of cancer

Ultrasound Imaging
Optical and opto-acoustic imaging.- Multifunctional magnetic imaging probes
Modern X-ray concepts-differential phase-contrast imaging
Pre-clinical SPECT and SPECT-CT.- Optical and photo-acoustic imaging.- Applications of small animal PET.- Preclinical molecular imaging using PET and MRI
Molecular ultrasound imaging
Advanced microscopy techniques
Mass spectroscopy
Quantitative SPECT-CT
Optical imaging of breast tumors and of gastrointestinal cancer by laser-induced fluorescence.- FDG PET and PET-CT.- Non-FDG PET-CT
Clinical MR biomarkers
Clinical PET-MR
Advanced ultrasound imaging
Radiomics and Radiogenomics
Cross validation techniques
Image-guided brain surgery
Image-guided abdominal surgery
Photon radiation therapy
Particle radiation therapy
Internal radiotherapy
Future challenges of multimodality imaging.