This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans.  It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials.  It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.

Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases

Ch 2: Sertoli cells: immunology and spermatogenesis
Ch 3: Innate immunity and spermatogenesis
Ch 4: Cell apoptosis and spermatogenesis
Ch 5: Transcriptional regulation of spermatogenesis
Ch 6: Sertoli cell cytoskeleton and spermatogenesis
Ch 7: Leydig cell and spermatogenesis
Ch 8: Cross-talk of cell junctions to support spermatogenesis
Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis
Ch 10: Regulation of the blood-testis barrier by basement membrane laminin- 2 chain
Ch 11: Regulation of spermatogenesis by collagens
Ch 12: Androgen regulation of spermatogenesis
Ch 13: Use of molecular modeling to study spermatogenesis
Ch 14: Acrosome biogenesis during spermatogenesis
Ch 15: Stem cells and spermatogenesis
Ch 16: Advances in our understanding of spermatogenesis in humans
Ch 17: Leydig cell function in aging men
Ch 18: Regulation of human spermatogenesis.